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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

別名:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Species:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...詳細
UniProtKB ID:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
遺伝子ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
M2547
8-メトキシメチル-3-イソブチル-1-メチルキサンチン, ≥98%,
Species
human
V6383
ビンポセチン, ≥98%, solid,
Species
human
1220506
ジピリダモール, United States Pharmacopeia (USP) Reference Standard,
Species
human
Y0000802
ジピリダモール, European Pharmacopoeia (EP) Reference Standard,
Species
human
D2850000
ジピリダモール, European Pharmacopoeia (EP) Reference Standard,
Species
human

esiRNA

製品番号
詳細
Species
EHU074801
MISSION® esiRNA, targeting human PDE1A,
Species
human
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
Species
mouse