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Merck

PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

別名:
BMPG, MBP, MBP1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5553) Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(19074) proteoglycan 2, bone marrow
  • Rat(58826) proteoglycan 2, bone marrow
  • Horse(100062803) proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗好酸球主要塩基性タンパク質抗体、クローンBMK13, clone BMK13, Chemicon®, from mouse,
交差性
human
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-PRG2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PRG2,
Species
human