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Merck

PRMT6

protein arginine methyltransferase 6

別名:
HRMT1L6
Species:
UniProtKB ID:
遺伝子ID:
  • Human(55170) Summary: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
  • Mouse(99890) protein arginine N-methyltransferase 6
  • Rat(295384) protein arginine methyltransferase 6
  • domestic cat(101093626) protein arginine methyltransferase 6
  • domestic guinea pig(100725259) protein arginine methyltransferase 6
  • cow(540228) protein arginine methyltransferase 6
  • Thale Cress(821541) protein arginine N-methyltransferase 6
  • naked mole-rat(101715374) protein arginine methyltransferase 6
  • sheep(101119859) protein arginine methyltransferase 6
  • Zebrafish(448867) protein arginine methyltransferase 6
  • dog(490133) protein arginine methyltransferase 6

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗PRMT6抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
抗PRMT6抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, rat
アプリケーション
ChIP
western blot
Anti- PRMT6 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-PRMT6 Antibody, clone 1Z10L6, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
western blot
抗PRMT6抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, pig, rat
アプリケーション
ELISA
western blot

Proteins

製品番号
詳細
Species
PRMT6 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
PRMT6 ヒト, recombinant, expressed in FreeStyle 293-F cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PRMT6,
Species
human
MISSION® esiRNA, targeting mouse Prmt6,
Species
mouse