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Merck

PRPH2

peripherin 2 (retinal degeneration, slow)

別名:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
  • Mouse(19133) peripherin 2
  • Rat(25534) peripherin 2
  • domestic cat(727697) peripherin 2 (retinal degeneration, slow)
  • sheep(101109569) peripherin 2 (retinal degeneration, slow)
  • cow(280907) peripherin 2 (retinal degeneration, slow)
  • chicken(395899) peripherin 2 (retinal degeneration, slow)
  • naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
  • dog(403972) peripherin 2 (retinal degeneration, slow)
  • domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Peripherin Antibody, serum, Chemicon®,
交差性
bovine, human, mouse, pig, rat
アプリケーション
immunohistochemistry
western blot
Anti-Peripherin Antibody, clone 8G2, purified antibody, Chemicon®,
交差性
bovine, human, mouse, pig, rat
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
Anti-PRPH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-Peripherin-2 Antibody, clone 2B7, clone 2B7, from mouse,
交差性
bovine, mouse
アプリケーション
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
抗ペリフェリン-2抗体、クローン6B10.1, clone 6B10.1, from mouse,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PRPH2,
Species
human