PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
別名:
TBP1
Species:
Human PSMC3 (5702), Mouse Psmc3 (19182), Rat Psmc3 (29677), Zebrafish psmc3 (321947), chicken PSMC3 (423182), domestic guinea pig Psmc3 (100727371), naked mole-rat Psmc3 (101706267), sheep PSMC3 (101117873), Domestic Rabbit PSMC3 (100354000), cow PSMC3 (508448) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5702) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]
- Mouse(19182) proteasome (prosome, macropain) 26S subunit, ATPase 3
- Rat(29677) proteasome (prosome, macropain) 26S subunit, ATPase 3
- Zebrafish(321947) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- chicken(423182) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- domestic guinea pig(100727371) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- naked mole-rat(101706267) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- sheep(101117873) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- Domestic Rabbit(100354000) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- cow(508448) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- Horse(100051468) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- domestic cat(101095435) proteasome (prosome, macropain) 26S subunit, ATPase, 3
- dog(475980) proteasome (prosome, macropain) 26S subunit, ATPase, 3
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗PSMC3 (ab1) ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast
アプリケーション
western blot
抗PSMC3抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot