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Merck

RNF8

ring finger protein 8, E3 ubiquitin protein ligase

別名:
hRNF8
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9025) Summary: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
  • Mouse(58230) ring finger protein 8
  • Rat(361815) ring finger protein 8, E3 ubiquitin protein ligase
  • naked mole-rat(101703952) ring finger protein 8, E3 ubiquitin protein ligase
  • domestic guinea pig(100725403) ring finger protein 8, E3 ubiquitin protein ligase
  • sheep(101103680) ring finger protein 8, E3 ubiquitin protein ligase
  • chicken(421435) ring finger protein 8, E3 ubiquitin protein ligase
  • domestic cat(101082654) ring finger protein 8, E3 ubiquitin protein ligase
  • dog(481775) ring finger protein 8, E3 ubiquitin protein ligase
  • Zebrafish(404050) ring finger protein 8, E3 ubiquitin protein ligase
  • cow(515933) ring finger protein 8

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-RING finger protein 8 Antibody, from rabbit, purified by affinity chromatography,
交差性
chimpanzee, human, mouse, rhesus macaque
アプリケーション
immunocytochemistry
western blot
抗RNF8抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
抗RNF8 ウサギ宿主抗体, IgG fraction of antiserum,
交差性
bovine, horse, human, mouse, pig, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human RNF8,
Species
human