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Merck

TRAF1

TNF receptor-associated factor 1

別名:
EBI6, MGC:10353
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7185) Summary: The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(22029) TNF receptor-associated factor 1
  • Rat(687813) TNF receptor-associated factor 1
  • cow(540944) TNF receptor-associated factor 1
  • dog(612709) TNF receptor-associated factor 1
  • chicken(417123) TNF receptor-associated factor 1
  • Zebrafish(100148503) TNF receptor-associated factor 1
  • naked mole-rat(101710804) TNF receptor-associated factor 1
  • domestic guinea pig(100723139) TNF receptor-associated factor 1
  • sheep(101122077) TNF receptor-associated factor 1
  • Domestic Rabbit(100338847) TNF receptor-associated factor 1
  • domestic cat(101087620) TNF receptor-associated factor 1
  • Horse(100067681) TNF receptor-associated factor 1

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-TRAF1 Antibody, clone 1F3, clone 1F3, from rat,
交差性
human, monkey
アプリケーション
flow cytometry
immunohistochemistry

western blot
抗TRAF1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-TRAF1 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunoprecipitation (IP)

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TRAF1,
Species
human
MISSION® esiRNA, targeting mouse Traf1,
Species
mouse