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Merck

UBE2D2

ubiquitin-conjugating enzyme E2D 2

別名:
E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7322) Summary: Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  • Rat(641452) ubiquitin-conjugating enzyme E2D 2
  • cow(541003) ubiquitin-conjugating enzyme E2D 2
  • chicken(416137) ubiquitin-conjugating enzyme E2D 2
  • domestic cat(101092081) ubiquitin-conjugating enzyme E2D 2
  • domestic guinea pig(100732779) ubiquitin-conjugating enzyme E2D 2
  • naked mole-rat(101724153) ubiquitin-conjugating enzyme E2D 2
  • dog(612742) ubiquitin-conjugating enzyme E2D 2

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-UBE2D2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot

Proteins

製品番号
詳細
Species
UbcH5b Conjugating Enzyme, 100 µg, The His6-tagged fusion protein of UbcH5b is charge & support ubiquitinylation in vitro. The His6-tagged UbcH5 family members all appear to form thiol ester conjugates with ubiquitin at a similar rate under similar conditions.,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human UBE2D2,
Species
human