UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
別名:
HUPF1, NORF1, RENT1, pNORF1, smg-2
Species:
Human UPF1 (5976), Mouse Upf1 (19704), Rat Upf1 (684558), Horse UPF1 (100071059), cow UPF1 (532933), Zebrafish upf1 (406783), chicken UPF1 (420119), domestic cat UPF1 (101096043), naked mole-rat Upf1 (101704366), fruit fly Upf1 (32153) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5976) Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19704) UPF1 regulator of nonsense transcripts homolog (yeast)
- Rat(684558) UPF1 regulator of nonsense transcripts homolog (yeast)
- Horse(100071059) UPF1 regulator of nonsense transcripts homolog (yeast)
- cow(532933) UPF1 regulator of nonsense transcripts homolog (yeast)
- Zebrafish(406783) upf1 regulator of nonsense transcripts homolog (yeast)
- chicken(420119) UPF1 regulator of nonsense transcripts homolog (yeast)
- domestic cat(101096043) UPF1 regulator of nonsense transcripts homolog (yeast)
- naked mole-rat(101704366) UPF1 regulator of nonsense transcripts homolog (yeast)
- fruit fly(32153) CG1559 gene product from transcript CG1559-RA
- sheep(101107598) UPF1 regulator of nonsense transcripts homolog (yeast)
- dog(476664) UPF1 regulator of nonsense transcripts homolog (yeast)
- domestic guinea pig(100713813) UPF1 regulator of nonsense transcripts homolog (yeast)
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗リン酸化Upf1（Ser1127）抗体, from rabbit, purified by affinity chromatography,
交差性
bovine, chicken, human, mouse, rat, yeast, zebrafish
アプリケーション
immunoprecipitation (IP)
western blot
western blot
Anti-p-Upf1 (Ser1127) Antibody, clone 1C4-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry
inhibition assay
western blot
immunocytochemistry
inhibition assay
western blot
抗UPF1抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Goat anti-RENT1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
交差性
human, mouse
アプリケーション
immunoprecipitation (IP)
western blot
western blot