329878

Sigma-Aldrich

水-18O

(for PET), 97 atom % 18O

別名:
18O水
化学式:
H218O
CAS番号:
分子量:
20.02
MDL番号:
PubChem Substance ID:
NACRES:
NA.12

品質水準

200

詳細

Normalized with respect to hydrogen

同位体純度

97 atom % 18O

アプリケーション

PET imaging: suitable

bp

100 °C (lit.)

mp

0 °C (lit.)

密度

1.11 g/mL at 20 °C (lit.)

適合性

(for PET)

質量シフト

M+2

SMILES string

[18OH2]

InChI

1S/H2O/h1H2/i1+2

InChI key

XLYOFNOQVPJJNP-NJFSPNSNSA-N

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関連するカテゴリー

アプリケーション

水-18Oは同位体で修飾された水で、PETでの使用に適します。
他に以下の用途があります:
  • 古気候学、水文学、および植物生態学において、植物セルロースの土壌安定性酸素同位体解析をδ18Oを使用して測定するため
  • 水分の結晶への拡散を二次イオン質量分析法(SIMS)を用いて測定するため

包装

250 mg in serum bottle
1 g in serum bottle
この製品は、バルク容量での利用が可能で、必要に応じてパッケージ化できます。価格、入手可能性、および梱包の情報については、Stable Isotopes Customer Serviceにお問い合わせください。
セプタム付き密閉血清ボトル入り。

storage_class_code

10 - Combustible liquids

ドイツ水質汚染分類

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

試験成績書(COA)

原産地証明書(COO)

Christian Berk et al.
FEBS letters, 595(2), 230-240 (2020-10-29)
Identifying the targetome of a microRNA is key for understanding its functions. Cross-linking and immunoprecipitation (CLIP) methods capture native miRNA-mRNA interactions in cells. Some of these methods yield small amounts of chimeric miRNA-mRNA sequences via ligation of 5'-phosphorylated RNAs produced...
Xueyan Cao et al.
Food chemistry, 276, 266-273 (2018-11-10)
Milk glycoproteins are crucial nutrients with a variety of functions. However, whey N-glycoproteomes in human and bovine milks have not been characterized during lactation. Herein, using lectin enrichment and liquid chromatography tandem mass spectrometry, 68, 58, 100, and 98 N-glycoproteins...
Diffusion of Water Species in Yttria-Stabilized Zirconia
Duong T, et al.
Journal of the American Chemical Society, 92(11), 2731-2737 (2009)
Separating soil and leaf water 18O isotopic signals in plant stem cellulose
Sternberg, Leonel da Silveira Lobo and Anderson, William T and Morrison, Kanema
Geochimica et Cosmochimica Acta, 67(14), 2561-2566 (2003)
Andrew J Thompson et al.
Cell host & microbe, 27(5), 725-735 (2020-04-17)
Hemagglutinins (HAs) from human influenza viruses adapt to bind α2-6-linked sialosides, overcoming a receptor-defined species barrier distinct from the α2-3 specificity of avian virus progenitors. Additionally, human-adapted HAs gain glycosylation sites over time, although their biological function is poorly defined....
資料
By first labeling molecular oxygen and then body water with 18O in a rat, Lifson measured the 18O abundance in expired CO2 and found the oxygens in CO2 exchanged with the oxygen in water. Indeed, these two oxygen containing species were in rapid isotopic equilibrium due to the actions of what we now know is carbonic anhydrase (Lifson, 1966)
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関連コンテンツ
Labeled isotopes used as target materials in imaging have provided insights into the various mechanisms of human physiology and have lead to treatments for diseases. Water-18O is used for the production of 18F radionuclides, such as 18FDG (Fluoro-deoxyglucose). 18FDG used in PET and with other imaging technologies, such as CT/SPECT, has led to the diagnosis and treatment of a wide range of diseases, including lung, liver, and brain tumors, epilepsy, and Alzheimer’s.
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