It is recommended to use these colloidal gold nanoparticles within the temperature range of 4°C to 25°C. Below 4°C, the particles will irreversibly aggregate and become unsuitable for further use. The upper limit for thermal stability has not been determined for these particles.
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品質水準
フォーム
nanoparticles
suspension
含みます
Proprietary Surfactant as stabilizer
濃度
~6.54E+11 particles/mL
OD
1
直径
20 nm
λmax
518-522 nm
PDI
<0.2
保管温度
2-8°C
SMILES記法
[Au]
InChI
1S/Au
InChI Key
PCHJSUWPFVWCPO-UHFFFAOYSA-N
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詳細
アプリケーション
オリゴヌクレオチドやポリエチレングリコールなどのチオール化リガンドの吸着に適しています。また、高い安定性を有することから、この金ナノ粒子は物理的、光学的用途への利用も可能です。注意：この製品はタンパク質吸着への利用には適していません。タンパク質やその他リガンドの吸着には、「gold nanoparticles stabilized in PBS」製品が最適です。
この材料は極めて高い単分散性(サイズと形状の変動係数：<12%)を示し、表面の反応性が大幅に向上しています。その応用例は、表面増強型ラマン散乱ナノプローブ、センサ/検出、生物学的ターゲティング、プラズモンナノ構造、およびナノスケールパターニングなどがあります。
この材料は極めて高い単分散性(サイズと形状の変動係数：<12%)を示し、表面の反応性が大幅に向上しています。その応用例は、表面増強型ラマン散乱ナノプローブ、センサ/検出、生物学的ターゲティング、プラズモンナノ構造、およびナノスケールパターニングなどがあります。
法的情報
CytoDiagnostics社の製品です。
保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
741965-100ML:
741965-25ML:
741965-100ML-PW:
741965-BULK:
741965-25ML-PW:
741965-VAR:
この製品を見ている人はこちらもチェック
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?
Alkilany AM and Murphy CJ
Journal of Nanoparticle Research, 12(7), 2313-2333 (2010)
Gold-Organic-Inorganic High-Surface-Area Materials as Precursors of Highly Active Catalysts
Budroni G and Corma A
Angewandte Chemie (International ed. in English), 45(20), 3328-3331 (2006)
Evaluation of novel Fmoc-tripeptide based hydrogels as immobilization supports for electrochemical biosensors
Fusco G, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 137(24), 105-110 (2018)
Biomedical applications of gold nanoparticles
Cabuzu D, et al.
Current Topics in Medicinal Chemistry, 15(16), 1605-1613 (2015)
Enhanced thermomechanical properties of a nematic liquid crystal elastomer doped with gold nanoparticles
Montazami R, et al.
Sensors and actuators A, Physical, 178(11), 175-178 (2012)
資料
Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.
ラテラルフロー免疫測定の感度を大幅に向上させる金ナノシェルのユニークな光学特性に基づく超高輝度レポーター粒子の使用について解説します。
Sustainable energy sources with high production efficiency are crucial for meeting increasing energy demand.
高い生産効率を有する持続可能なエネルギー源は、高まるエネルギー需要を満たすために極めて重要です。
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What is the recommended temperature range for using your 10 nm gold nanoparticles? Additionally, is there a temperature limit beyond which they may aggregate or lose stability?
1 回答-
役に立ちましたか？
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf役に立ちましたか？
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
役に立ちましたか？
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The AuNPs in citrate do not change color when with NaCl. What can I do? Do you have any recommendation of what protocol can I use to functionalize citrate AuNPs 20nm?
1 回答-
The color change of AuNPs when mixed with NaCl is typically due to the aggregation of AuNPs. However, this product contains citrate buffer as a stabilizer, so a small amount of NaCl will not lead to aggregation. Increasing the amount of NaCl or performing a solvent exchange to remove the citrate buffer may induce a color change, but this is not recommended as the aggregated AuNPs may not be able to be re-dispersed. Unfortunately, no protocol is available to functionalize the AuNPs.
役に立ちましたか？
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What is the molarity of this solution (ref: 741965)?"
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The concentration for this product is listed as ~6.54E+11 particles/mL. The concentration in g/mol is not determined.
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My solution of 5nm gold nanoparticles has turned from red to purple. This would indicate aggregation. What caused this and how can I reverse the aggregation? The nanoparticles are stored in a fridge at 5 degrees C.
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The information below regarding the color change and aggregation is provided by the manufacturer:
The gold nanoparticle solution turns violet when I add salt-containing buffer. Why is that?
Due to repulsive forces arising from the surface charge of gold nanoparticles, an energy barrier must be overcome for individual particles to interact.
When no (or small) amounts of electrolytes such as NaCl are present, this energy barrier is too strong for interaction to occur between particles. However, upon the addition of NaCl, this energy barrier is reduced allowing the gold nanoparticles to interact and aggregate. This aggregation causes a phenomenon called surface-plasmon coupling which changes the adsorption maximum of light to a higher wavelength resulting in a change in the color of the solution.Gold Nanoparticle Aggregation
The aggregation state of gold nanoparticles has an effect on their optical properties. This fact can be used to monitor gold nanoparticle stability, both over time, and upon the addition of salt-containing buffers, which at high enough concentrations cause particle aggregation, figure 5. The red-shift in absorption maximum caused by aggregation, or particles in close proximity, has successfully been utilized in many assays as a detection mechanism.See the image below for details on the effects of aggregation on color change and wavelength.
To discuss this further, please we kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice and click on "Report Product Issues" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.
役に立ちましたか？
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Which technique is used for the synthesis of these Gold nanoparticles?
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This product has a quality level 100. The preparation and synthesis is proprietary for products with a quality level under 400.
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My gold nanoparticles settle out of solution upon storage. Is this normal?
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Settling of gold nanoparticles on the bottom of the storage flask is completely normal and is especially common for larger sized particles, which settles at greater speed. Settling does not affect the performance of the particles. Prior to use, simply swirl the solution to properly disperse your gold nanoparticles and obtain a homogenous solution.
役に立ちましたか？
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Why does my gold nanoparticle solution turn violet when I add salt containing buffer?
1 回答-
Due to repulsive forces arising from the surface charge of gold nanoparticles, an energy barrier must be overcome for individual particles to interact. When no (or small) amounts of electrolytes such as NaCl is present, this energy barrier is too strong for interaction to occur between particles. However, upon addition of NaCl this energy barrier is reduced allowing the gold nanoparticles to interact and aggregate. This aggregation causes a phenomenon called surface-plasmon coupling which changes the adsorption maximum of light to a higher wavelength resulting in a change in color of the solution.
役に立ちましたか？
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What is the Department of Transportation shipping information for this product?
1 回答-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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