This product may be stored at room temperature.
N21804
3-ニトロフェニルヒドラジン 塩酸塩
98%
別名:
(3-Nitrophenyl)hydrazine hydrochloride, 1-(3-Nitrophenyl)hydrazine hydrochloride, 3-Nitrophenylhydrazine monohydrochloride, m-Nitrophenylhydrazine hydrochloride
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この商品について
化学式:
O2NC6H4NHNH2 · HCl
CAS番号:
分子量:
189.60
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-270-6
MDL number:
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製品名
3-ニトロフェニルヒドラジン 塩酸塩, 98%
InChI key
BKOYKMLGFFASBG-UHFFFAOYSA-N
InChI
1S/C6H7N3O2.ClH/c7-8-5-2-1-3-6(4-5)9(10)11;/h1-4,8H,7H2;1H
SMILES string
Cl.NNc1cccc(c1)[N+]([O-])=O
assay
98%
form
powder
mp
210 °C (dec.) (lit.)
Quality Level
関連するカテゴリー
1 of 4
当該品目 | 153958 | 100358 | 415723 |
|---|---|---|---|
| assay 98% | assay 98% | assay 98% | assay 98% |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| form powder | form - | form solid | form solid |
| mp 210 °C (dec.) (lit.) | mp 227-231 °C (dec.) (lit.) | mp 321-323 °C (dec.) (lit.) | mp - |
Application
<ul>
<li><strong>分析化学における誘導体化剤：</strong>3-ニトロフェニルヒドラジン塩酸塩は、単純ヘルペスウイルス 1 型に感染した生物学的サンプル中のγ-ヒドロキシ酪酸の測定における誘導体化剤として用いられ、LC-MRM-MS 技術を活用することで、法医学および臨床毒物学における検出能力の向上を実現しています（Osinaga et al., 2022）。</li>
<li><strong>製薬製剤における残留分析：</strong>この化合物は、3-ニトロフェニルヒドラジンによる誘導体化後に UV/Vis 検出器付き HPLC を用いて、クロラムフェニコールおよびその製剤中の残留 4-ニトロベンズアルデヒドの定量分析にも使用されており、医薬品の純度と安全性を確保するための信頼性の高い方法を提供しています（Luo et al., 2018）。</li>
<li><strong>分解物分析における法医学的応用：</strong>法医学的解剖時に採取した血液サンプルの誘導体化に使用されています（Matoba et al., 2022）。</li>
</ul>
<li><strong>分析化学における誘導体化剤：</strong>3-ニトロフェニルヒドラジン塩酸塩は、単純ヘルペスウイルス 1 型に感染した生物学的サンプル中のγ-ヒドロキシ酪酸の測定における誘導体化剤として用いられ、LC-MRM-MS 技術を活用することで、法医学および臨床毒物学における検出能力の向上を実現しています（Osinaga et al., 2022）。</li>
<li><strong>製薬製剤における残留分析：</strong>この化合物は、3-ニトロフェニルヒドラジンによる誘導体化後に UV/Vis 検出器付き HPLC を用いて、クロラムフェニコールおよびその製剤中の残留 4-ニトロベンズアルデヒドの定量分析にも使用されており、医薬品の純度と安全性を確保するための信頼性の高い方法を提供しています（Luo et al., 2018）。</li>
<li><strong>分解物分析における法医学的応用：</strong>法医学的解剖時に採取した血液サンプルの誘導体化に使用されています（Matoba et al., 2022）。</li>
</ul>
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Derivatization of N-acyl glycines by 3-nitrophenylhydrazine for targeted metabolomics analysis and their application to the study of diabetes progression in mice
Xiang, Li and Ru, et al.
Analytical Chemistry, 95, 2183-2191 (2023)
Lin-Xiu Guo et al.
Molecules (Basel, Switzerland), 25(23) (2020-12-10)
Short-chain fatty acids (SCFAs) are the main microbial fermentation products from dietary fibers in the colon, and it has been speculated that they play a key role in keeping healthy in the whole-body. However, differences in SCFAs concentration in the
François-Xavier Danlos et al.
Cell death & disease, 12(3), 258-258 (2021-03-13)
The circulating metabolome provides a snapshot of the physiological state of the organism responding to pathogenic challenges. Here we report alterations in the plasma metabolome reflecting the clinical presentation of COVID-19 patients with mild (ambulatory) diseases, moderate disease (radiologically confirmed
Isotope-labeling derivatization with 3-nitrophenylhydrazine for LC/multiple-reaction monitoring-mass-spectrometry-based quantitation of carnitines in dried blood spots
Han, Jun and Higgins, et al.
Analytica Chimica Acta, 1037, 177-187 (2018)
Michele Dei Cas et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1154, 121982-121982 (2020-08-31)
Short and medium fatty acids derived from either dietary sources, gut microbiota, and liver production might play a role in the modulation of metabolism and inflammation. The outcome of different autoimmune or inflammatory diseases could be related to microbiota composition
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What is the storage temperature?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf役に立ちましたか？
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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