700029P

3β,7β-dihydroxy-5-cholestenoic acid

Avanti Research^™ - A Croda Brand

• 別名: (25R)-cholest-5-en-26-oic acid, 3β,7β-hydroxy
• 実験式（ヒル表記法）: C₂₇H₄₄O₄
• CAS Number: 1246298-66-7
• 分子量: 432.64
• MDL番号: MFCD22416723
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: powder
• 包装: pkg of 1 × 1 mg (700029P-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 輸送温度: dry ice
• 保管温度: −20°C

詳細

詳細

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) is associated with plasma and is a C27 acid.[1] 3β,7β-diHCA is synthesized from 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid (3βH,7O-CA) by the action of the enzyme hydroxysteroid 11-β dehydrogenase 1.[2]

アプリケーション

3β,7β-dihydroxy-5-cholestenoic acid may be used as an authentic diastereoisomer standard in mass spectrometry (MS) experiments.[3]

生物化学的／生理学的作用

3β,7β-dihydroxy-5-cholestenoic acid (3β,7β-diHCA) levels are elevated in Niemann-Pick type C (NPC) disease and Niemann-Pick (NP) disease type B disorders.[1] It elicits toxicity to oculomotor neurons.[2]

包装

5 mL Amber Glass Screw Cap Vial (700029P-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids