Merck
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資料

700172P

Avanti

cholesterol-d6

Avanti Polar Lipids 700172P, powder

すべての画像(1)
別名:
cholesterol-d6
Empirical Formula (Hill Notation):
C27H40D6O
CAS番号:
60816-17-3
分子量:
392.69
NACRES:
NA.25

アッセイ

>99% (TLC)

形状

powder

包装

pkg of 1 × 10 mg (700172P-10mg)

manufacturer/tradename

Avanti Polar Lipids 700172P

輸送温度

dry ice

保管温度

−20°C

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当該品目
700041P700137P700040P
cholesterol-d6 Avanti Polar Lipids 700172P, powder

Avanti

700172P

cholesterol-d6

cholesterol-d7 Avanti Polar Lipids

Avanti

700041P

コレステロール-d7

7β,27-dihydroxycholesterol-d6 Avanti Polar Lipids 700137P, powder

Avanti

700137P

7β,27-dihydroxycholesterol-d6

desmosterol-d6 Avanti Polar Lipids

Avanti

700040P

デスモステロール-d6

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 10 mg (700172P-10mg)

packaging

pkg of 1 × 10 mg (700041P-10mg), pkg of 1 × 200 mg (700041P-200mg), pkg of 1 × 25 mg (700041P-25mg), pkg of 1 × 50 mg (700041P-50mg)

packaging

pkg of 1 × 1 mg (700137P-1mg)

packaging

pkg of 1 × 1 mg (700040P-1mg)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

manufacturer/tradename

Avanti Polar Lipids 700172P

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 700137P

manufacturer/tradename

Avanti Polar Lipids

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

詳細

Cholesterol-d6 is a deuterium labelled cholesterol. Ring labelled D6-cholesterol forms D6-steroidal glycoalkaloids (SGA).
Cholesterol-d6 is the deuterated cholesterol with deuteration in ring.

アプリケーション

Cholesterol-d6 is suitable for its use as a synthetic lipid standard, for cholesterol determination.
Cholesterol-d6 is used as a standard to detect cholesterol concentration using chromatography technique. It is also used to measure the percentage of cholesterol absorption by intravenously administrating into experimental animals.
Cholesterol-d6 may be used as an internal standard in
  • electrospray ionization tandem mass spectrometry (ESIMS/MS)
  • gas chromatography–mass spectrometry (GC-MS)
  • for spiking lipid extracts from Drosophila for liquid chromatography–mass spectrometry (LC-MS)

生物化学的／生理学的作用

Cholesterol-d6 rich liposomes are used in understanding the kinetics of reverse cholesterol transport in lymphatic and aorta. It is used in the generation of stratum corneum (SC) lipid model systems for deuteration based neutron diffraction studies. Use of Cholesterol-d6 as a diet supplement has enabled the understanding cholesterol metabolism in the blood brain barrier.

包装

5 mL Amber Glass Screw Cap Vial (700172P-10mg)

保管分類コード

11 - Combustible Solids

WGK

WGK 1

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  • もしTO09019TOなどのロット番号を見つけた場合は、最初の2文字を除いたロット番号09019TOを入力します。

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JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
Singh K, et al.
Nature Communications, 9(1), 3425-3425 (2018)
Biochemical membrane lipidomics during Drosophila development
Guan XL, et al.
Developmental Cell, 24(1), 98-111 (2013)
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain
Saeed AA, et al.
The Journal of Biological Chemistry, 289(34), 23712-23722 (2014)
The tumor suppressor TERE1 (UBIAD1) prenyltransferase regulates the elevated cholesterol phenotype in castration resistant prostate cancer by controlling a program of ligand dependent SXR target genes
Fredericks WJ, et al.
Testing, 4(7), 1075-1075 (2013)
Central leptin regulates total ceramide content and sterol regulatory element binding protein-1C proteolytic maturation in rat white adipose tissue
Bonzon-Kulichenko E, et al.
Endocrinology, 150(1), 169-178 (2008)
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