Merck

850101P

Avanti

13:0 Lyso PI

1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

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別名:
PI(13:0/0:0); 110716
Empirical Formula (Hill Notation):
C22H46NO12P
CAS番号:
分子量:
547.57
NACRES:
NA.25

アッセイ

>99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)

形状

powder

包装

pkg of 1 × 100 μg (with stopper and crimp cap (850101P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850101P-500ug))

manufacturer/tradename

Avanti Polar Lipids 850101P

lipid type

phospholipids
cardiolipins

輸送温度

dry ice

保管温度

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCC)=O.[NH4+]

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当該品目
850102P850103P850104P
13:0 Lyso PI 1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Avanti

850101P

13:0 Lyso PI

16:0 Lyso PI 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

Avanti

850102P

16:0リゾPI

17:1 Lyso PI 1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

Avanti

850103P

17:1リゾPI

18:0 Lyso PI 1-stearoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt), powder

Avanti

850104P

18:0 Lyso PI

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850101P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850101P-500ug))

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug))

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850103P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850103P-500ug))

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850104P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850104P-500ug))

manufacturer/tradename

Avanti Polar Lipids 850101P

manufacturer/tradename

Avanti Polar Lipids 850102P

manufacturer/tradename

Avanti Polar Lipids 850103P

manufacturer/tradename

Avanti Polar Lipids 850104P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

詳細

Lysophosphatidylinositol (LPI), produced by phospholipase A2 is a bioactive lipid.

アプリケーション

13:0 Lyso PI (1-tridecanoyl-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) may be used as a nonendogenous phospholipid (PL) standard for the quantitative analysis of PLs. It may also be used as a standard for tandem mass spectrometry analysis of lipid species in human plasma.

生物化学的/生理学的作用

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) is expected to play a vital role in various diseases. Ca2+ channels at the plasma membrane and mitochondrial membrane are controlled by LPI. It can also stimulate various signaling pathways to control several cellular processes. LPI can block the migration of cells.

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850101P-500ug)

保管分類コード

11 - Combustible Solids


試験成績書(COA)

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705578-5MG-PW

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COAをリクエストする

Roberto Piñeiro et al.
Biochimica et biophysica acta, 1821(4), 694-705 (2012-01-31)
Lysophosphatidylinositol (LPI) is a bioactive lipid generated by phospholipase A2 which is believed to play an important role in several diseases. Indeed LPI can affect various functions such as cell growth, differentiation and motility, in a number of cell-types, including
Shuang Song et al.
Food chemistry, 240, 1171-1178 (2017-09-28)
Nuts, a class of fatty natural food, are associated with a series of health benefit. Lipid, which is the most abundant nutrient in nuts, could be one of the major contributors to many beneficial effects. In previous studies, only the
Kevin Huynh et al.
Cell chemical biology, 26(1), 71-84 (2018-11-13)
High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-MS) has been used extensively to identify associations between plasma lipid species and disease states. Such methods, used to characterize larger clinical cohorts, often suffer from an inability to differentiate isomeric forms
David B Iaea et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(4), 158609-158609 (2020-01-10)
STARD4, a member of the evolutionarily conserved START gene family, is a soluble sterol transport protein implicated in cholesterol sensing and maintenance of cellular homeostasis. STARD4 is widely expressed and has been shown to transfer sterol between liposomes as well

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