Merck

850371P

Avanti

22:0 PC

1,2-dibehenoyl-sn-glycero-3-phosphocholine, powder

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別名:
1,2-didocosanoyl-sn-glycero-3-phosphocholine; PC(22:0/22:0)
実験式(ヒル表記法):
C52H104NO8P
CAS番号:
分子量:
902.36
NACRES:
NA.25

アッセイ

>99% (TLC)

形状

powder

包装

pkg of 1 × 1 g (850371P-1g)
pkg of 1 × 25 mg (850371P-25mg)
pkg of 1 × 500 mg (850371P-500mg)

メーカー/製品名

Avanti Polar Lipids 850371P

脂質タイプ

phospholipids
cardiolipins

輸送温度

dry ice

保管温度

−20°C

SMILES記法

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C52H104NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-40-42-44-51(54)58-48-50(49-60-62(56,57)59-47-46-53(3,4)5)61-52(55)45-43-41-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h50H,6-49H2,1-5H3

InChI Key

HRTBOPUWPUXROO-UHFFFAOYSA-N

類似品目との比較

比較内容をすべて表示

相違点を表示

1 of 4

当該品目
850368P850371C850368C
22:0 PC 1,2-dibehenoyl-sn-glycero-3-phosphocholine, powder

850371P

22:0 PC

20:0 PC 1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

850368P

20:0 PC

22:0 PC 1,2-dibehenoyl-sn-glycero-3-phosphocholine, chloroform

850371C

22:0 PC

20:0 PC 1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

850368C

20:0 PC

packaging

pkg of 1 × 1 g (850371P-1g), pkg of 1 × 500 mg (850371P-500mg), pkg of 1 × 25 mg (850371P-25mg)

packaging

pkg of 1 × 200 mg (850368P-200mg), pkg of 1 × 25 mg (850368P-25mg), pkg of 1 × 500 mg (850368P-500mg)

packaging

pkg of 1 × 2.5 mL (850371C-25mg), pkg of 1 × 20 mL (850371C-500mg)

packaging

pkg of 1 × 2.5 mL (850368C-25mg)

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

manufacturer/tradename

Avanti Polar Lipids 850371P

manufacturer/tradename

Avanti Polar Lipids 850368P

manufacturer/tradename

Avanti Polar Lipids 850371C

manufacturer/tradename

Avanti Polar Lipids 850368C

form

powder

form

powder

form

liquid

form

liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

詳細

Phosphatidylcholines (PCs) are amphipathic molecules, that are mainly located on the outer leaflets of the biological membrane bilayer. Approximately 40–50% of the total cellular phospholipids consists of phosphatidylcholine.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

アプリケーション

22:0 PC may be used:
  • to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP)/α-secretase activity
  • to prepare a lipid monolayer to study whether ligand is specifically targeted to domains containing Cu(II)-iminodiacetate lipid (Cu-PSIDA)
  • as a lipid standard for the quantification of lipid species from lipid droplets by hydrophilic interaction liquid chromatography-high performance liquid chromatography (HILIC-HPLC)

生物化学的/生理学的作用

Phosphatidylcholines (PCs) can serve as lung surfactant.

包装

20 mL Clear Glass Screw Cap Vial (850371P-1g)
20 mL Clear Glass Screw Cap Vial (850371P-500mg)
5 mL Amber Glass Screw Cap Vial (850371P-25mg)

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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K Maloney et al.
Chemistry & biology, 3(3), 185-192 (1996-03-01)
Chemical information is sometimes transmitted across cell membranes by ligand-induced assembly of receptors. We have previously designed a series of lipids with metal-chelating headgroups that can serve as general receptors for proteins containing accessible histidines. Such lipids can also be
Elinor Thompson et al.
Healthcare technology letters, 6(5), 138-142 (2019-12-14)
Oxygen loaded microbubbles are being investigated as a means of reducing tumour hypoxia in order to improve response to cancer therapy. To optimise this approach, it is desirable to be able to measure changes in tissue oxygenation in real-time during
Estelle Beguin et al.
Journal of controlled release : official journal of the Controlled Release Society, 317, 23-33 (2019-11-17)
Recent pre-clinical studies have demonstrated the potential of combining chemotherapy and sonodynamic therapy for the treatment of pancreatic cancer. Oxygen-loaded magnetic microbubbles have been explored as a targeted delivery vehicle for this application. Despite preliminary positive results, a previous study
Pinunta Nittayacharn et al.
Frontiers in pharmacology, 11, 644-644 (2020-06-02)
Drug delivery to solid tumors using echogenic nanobubbles (NBs) and ultrasound (US) has recently gained significant interest. The approach combines attributes of nanomedicine and the enhanced permeation and retention (EPR) effect with the documented benefits of ultrasound to improve tumor
Bingbing Cheng et al.
Scientific reports, 9(1), 20020-20020 (2019-12-29)
Real-time acoustic feedback control based on harmonic emissions of stimulated microbubbles may be important for facilitating the clinical adoption of focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening, both to ensure safe acoustic exposures, and to achieve repeatable and consistent opening.

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