Merck
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C-113

Supelco

Cortisol-D4 (9,11,12, 12-D4) 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):
コルチゾール-D4 (9,11,12,12-D4) 溶液, ヒドロコルチゾン-9,11,12,12-D4 溶液
Empirical Formula (Hill Notation):
C21H26D4O5
CAS Number:
Molecular Weight:
366.48
EC 番号:
MDL番号:
PubChem Substance ID:
NACRES:
NA.24

グレード

certified reference material

品質水準

300

形状

liquid

特徴

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

manufacturer/tradename

Cerilliant®

濃度

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

フォーマット

single component solution

保管温度

−20°C

SMILES string

[2H]C1([2H])[C@]([2H])(O)[C@@]2([2H])[C@@H](CCC3=CC(=O)CC[C@]23C)[C@@H]4CCC(O)(C(=O)CO)[C@@]14C

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1/i10D2,16D,18D

InChI key

JYGXADMDTFJGBT-BJJKTIQHSA-N

詳細

コルチゾール(別名ヒドロコルチゾン)は、副腎が生産する糖質コルチコイドです。この安定性のある標識された内部標準は、先天性副腎過形成 (CAH) の新生児スクリーニングを目的としたLC-MS/MS (液体クロマトグラフィー質量分析法) による全血中コルチゾール濃度の定量化、および、クッシング症候群、アジソン病、およびシーハン症候群を含む、いくつかの疾患の判定を目的としたLC-MS/MSによる血清または血漿中濃度の定量化に適しています。

アプリケーション

This Certified Spiking Solution® is suitable for GC/MS and LC/MS applications from clinical and diagnostic testing and endocrinology to sports testing.The Certified Reference Material (CRM) in solution can also be used as an internal standard as follows:
  • Identification of cortisol by atmospheric pressure chemical ionization (APCI) and selected reaction monitoring (SRM) during the high-performance liquid chromatography- tandem mass spectrometric (HPLC-MS/MS) analysis of cortisol in human sweat samples
  • Combined determination of cortisol and cortisone in 48 serum samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • Development and validation of an LC-MS/MS method to determine five steroids― free cortisol, cortisone, tetrahydrocortisol, allo-tetrahydrocortisol, and tetrahydrocortisone in urine samples
  • Multi-residue analysis of cortisol, cortisone, and dehydroepiandrosterone sulfate (DHEAS) in 103 hair samples by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-MS/MS)
  • Rapid LC-MS/MS-based assay of cortisol in 2860 serum samples over a duration of one year, using a simple protein precipitation technique for sample preparation

特徴および利点

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

法的情報

CERILLIANT is a registered trademark of Cerilliant Corporation
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

ピクトグラム

FlameSkull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

保管分類コード

3 - Flammable liquids

WGK

WGK 1

引火点(°F)

49.5 °F - closed cup

引火点(℃)

9.7 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C-113-1ML:4548173314860

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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