116833

Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC).

• 別名: Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt, 8-CPT-2ʹ-O-Me-cAMP, Na
• 実験式（ヒル表記法）: C₁₇H₁₆ClN₅O₆PS · Na
• 分子量: 507.82
• UNSPSCコード: 12352208

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic)
• 溶解性: water: 10 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) (also called cAMP-guanine nucleotide-exchange factors or cAMP-GEF) in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. 5 µmol = 2.54 mg. λmax = 282 nm.

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA.

Note: 5 µmol = 2.54 mg.

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

その他情報

Kang, G., et al. 2003. J. Biol. Chem.278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.

法的情報

Sold under license of European Patent Application 02/077,219.0.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable