Merck
  • 200100
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200100

Sigma-Aldrich

Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside

Used as an inhibitor of O-linked glycosylation in a variety of cell lines.

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Synonym(s):
Benzyl-2-acetamido-2-deoxy-α-D-galactopyranoside, Benzyl-α-GalNAc
Empirical Formula (Hill Notation):
C15H21NO6
CAS Number:
3554-93-6
Molecular Weight:
311.33
MDL番号:
MFCD00057920

アッセイ

≥98% (TLC)

形状

solid

manufacturer/tradename

Calbiochem®

保管条件

OK to freeze

色

off-white

溶解性

hot ethanol: 1 mg/mL
DMSO: 100 mg/mL

輸送温度

ambient

保管温度

−20°C

SMILES string

CC(N[C@H]([C@H]([C@H]1O)O)[C@H](O[C@@H]1CO)OCC2=CC=CC=C2)=O

InChI

1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13+,14-,15+/m1/s1

InChI key

SKOZFDIGKDPQBO-QMIVOQANSA-N

詳細

Used as an inhibitor of O-linked glycosylation in a variety of cell lines. Also inhibits 2,3(O)-sialyltransferase and disrupts glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.
Used as an inhibitor of O-linked glycosylation in a variety of cell lines. It has also been used to inhibit 2,3(O)-sialyltransferase and disrupt glycoprotein targeting in HT-29 cells. Substrate for N-acetyl-β-D-glucosaminyltransferase.

生物化学的／生理学的作用

Cell permeable: no
Primary Target
o-linked glycosylation
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Standard Handling (A)

その他情報

Huet, G., et al. 1998. J. Cell Biol. 141, 1311.
Kuan, S.-F., et al. 1989. J. Biol. Chem. 264, 19271.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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