Merck
  • 495455
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495455

Sigma-Aldrich

Oligomycin

A mixture of A, B, and C isomers.

Synonym(s):
Oligomycin
Empirical Formula (Hill Notation):
C45H74O11
CAS Number:
Molecular Weight:
791.06
MDL番号:
NACRES:
NA.77

品質水準

アッセイ

≥90% (mixture of A, B, and C isomers, HPLC)

形状

powder

manufacturer/tradename

Calbiochem®

保管条件

OK to freeze

white

輸送温度

ambient

保管温度

10-30°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

InChI key

MNULEGDCPYONBU-ZUSSGZTJSA-N

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This Item
V0627PHR195075351
Oligomycin A mixture of A, B, and C isomers.

Sigma-Aldrich

495455

Oligomycin

Valinomycin ≥98% (TLC), ≥90% (HPLC)

Sigma-Aldrich

V0627

バリノマイシン

Spiramycin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1950

スピラマイシン

Oligomycin A ≥99% (HPLC)

Sigma-Aldrich

75351

オリゴマイシンA

assay

≥90% (mixture of A, B, and C isomers, HPLC)

assay

≥90% (HPLC), ≥98% (TLC)

assay

-

assay

≥99% (HPLC)

form

powder

form

powder

form

-

form

powder

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

storage condition

OK to freeze

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

storage condition

-

storage condition

-

color

white

color

white

color

-

color

white to off-white

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

詳細

A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.

生物化学的/生理学的作用

Cell permeable: no
Primary Target
Membrane-bound mitochondrial ATPase (F1)
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Irritant (B)

再構成

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.

その他情報

Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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