Merck
All Photos(1)

5.00528

Sigma-Aldrich

InhibitorSelect TLR Signaling Pathway Panel

All Photos(1)

形状

solid

manufacturer/tradename

Calbiochem®

保管条件

OK to freeze
desiccated (hygroscopic)
protect from light

保管温度

−20°C

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6143105.304095.30654
Sigma-Aldrich

Sigma-Aldrich

5.00528

InhibitorSelect TLR Signaling Pathway Panel

TLR3/dsRNA Complex Inhibitor The TLR3/dsRNA Complex Inhibitor blocks dsRNA binding to TLR3.

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614310

TLR3/dsRNA Complex Inhibitor

TLR8 Agonist, cpd14b

Sigma-Aldrich

5.30409

TLR8 Agonist, cpd14b

c-Rel Inhibitor, IT-603

Sigma-Aldrich

5.30654

c-Rel Inhibitor, IT-603

form

solid

form

solid

form

powder

form

powder

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage condition

OK to freeze, protect from light

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

詳細

A panel containing 16 potent, selective and cell-permeable inhibitors that is useful for the study of TLR signaling. This panel contains the following inhibitors and 15 ml anhydrous DMSO for reconstitution:
A panel containing 16 potent, selective and cell-permeable inhibitors that is useful for the study of TLR signaling: 1 mg of TIRAP Inhibitor Peptide, Cell-Permeable (>Cat. No. 613570), 10 mg of IL-1R Antagonist (>Cat. No. 407616), 5 mg of Interleukin-1 Receptor-Associated-Kinase-1/4 Inhibitor (Cat. No. 407601), 1 mg of (5Z)-7-Oxozeaenol, Curvularia sp. (Cat. No. 499610), 10 mg of BX-795 (Cat. No. 204001), 5 mg of NBD-Binding Peptide II, Cell Permeable, CTP-NBD (Cat. No. 480026), 25 mg of Cdc42/Rac1 GTPase Inhibitor, ML141 (Cat. No. 217708), 5 mg of PKR Inhibitor (Cat. No. 527450), 5 mg of LY294002 (Cat. No. 440202), 5 mg of U0126 (Cat. No. 662005), 1 mg of IKK Inhibitor VII (Cat. No. 401486), 10 mg of BAY 11-7082 (Cat. No. 196870), 1 mg of SB 203580 (Cat. No. 559389), 5 mg of SP600125 (Cat. No. 420119), 10 mg of STAT3 Inhibitor III, WP1066 (Cat. No. 573097), and 10 mg of MG-132 (Cat. No. 474787). Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817).

生物化学的／生理学的作用

Cell permeable: yes
Primary Target
Major hubs involved in TLR signaling cascade

包装

Packaged under inert gas

警告

Toxicity: Irritant (B)

再構成

Following reconstitution, aliquot and freeze (-20°C) each inhibitor. Each inhibitor solution is stable for up to 3 months at -20°C.
Please refer to information provided on the CD for reconstitution information of individual inhibitors.

その他情報

Aksoy, E., et al. 2012. Nat. Immunol.13, 1045.
Kondo, T., et al. 2012. Trends Immunol.33, 449.
Kawai, T. and Akira, S., 2010. Nat. Immunol.11, 373.
Kong, L. and Ge, B.X., 2008. Cell Res.18, 745.
Gilliet, M., et al. 2008. Nat. Rev. Immunol.8, 594.
Verstrepen, L., et al. 2008. Cell. Mol. Life Sci.65, 2964.
Wong, C.K., et al. 2007. Am. J. Respir. Cell Mol. Biol.37, 85.
Kawai, T. and Akira, S., 2007. Trends Mol. Med.13, 460.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

188.6 °F - (Dimethylsulfoxide)

引火点(℃)

87 °C - (Dimethylsulfoxide)

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

PDSCL

劇物

FSL

第4類:引火性液体
第三石油類
危険等級III
非水溶性液体

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