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Merck

PHR1073

1-(4-メトキシフェニル)-3-(4-tert-ブチルフェニル)-1,3-プロパンジオン

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

アボベンゾン, ブチルメトキシジベンゾイルメタン

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1 G

¥16,600

¥16,600


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この商品について

実験式(ヒル表記法):
C20H22O3
CAS番号:
分子量:
310.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
274-581-6
MDL number:

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製品名

1-(4-メトキシフェニル)-3-(4-tert-ブチルフェニル)-1,3-プロパンジオン, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

XNEFYCZVKIDDMS-UHFFFAOYSA-N

InChI

1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3

SMILES string

COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1045337

API family

avobenzone

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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1 of 4

当該品目
166331045337PHR1083
Avobenzone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1073

Avobenzone

Avobenzone analytical standard

Supelco

16633

Avobenzone

Avobenzone United States Pharmacopeia (USP) Reference Standard

USP

1045337

Avobenzone

Octocrylene Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1083

Octocrylene

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

format

neat

format

neat

format

neat

Quality Level

300

Quality Level

100

Quality Level

-

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

2-30°C

agency

traceable to USP 1045337

agency

-

agency

-

agency

traceable to USP 1477411

Application

これらの二次標準物質は、認定標準物質として適格性が認定されています。これらは、医薬品出荷試験、定性・定量分析のための医薬品方法開発、食品・飲料の品質管理試験、およびその他の校正要件など(ただし、これらに限らない)いくつかの分析用途での使用に適しています。
アボベンゾンは、医薬製剤中の分析物を逆相高速液体クロマトグラフィー法で測定する際に、医薬品標準物質として使用できます。[1]

General description

アボベンゾンは、日焼け止めローションおよび化粧品に使用される、日焼け止め有効成分です。[2]
品質管理に適用される医薬品の二次標準物質であり、医薬品の研究室および製造業者にとって、社内ワーキングスタンダードの調製に代わる便利でコスト効果の高い代替手段となります。

Other Notes

この物質の分析証明書の見本をご覧になるには、下のスロットにLRAB3693と入力してください。これは単に証明書サンプルであり、お客様が受け取るロットのものではない可能性があります。
この認証参照物質(CRM)は、ISO/IEC 17034およびISO/IEC 17025に準拠して製造・認証されました。このCRMの使用に関するすべての情報は分析証明書に記載されています。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Related product

hcodes

Hazard Classifications

Aquatic Chronic 4

保管分類

11 - Combustible Solids

wgk

WGK 2


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Development and validation of a new RP-HPLC method for the simultaneous determination of hydroquinone, kojic acid, octinoxate, avobenzone, BHA and BHT in skin-whitening cream.
Galimany-Rovira F, et al.
Analytical Methods : Advancing Methods and Applications, 8(5), 1170-1180 (2016)
Jing Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 605-612 (2008-01-30)
The objective of the present study was to determine the effects of hydroxypropyl-beta-cyclodextrin (HPCD) complexation on the transdermal penetration and photostability of a model ultraviolet A (UVA) absorber, butyl methoxydibenzoylmethane (avobenzone), and to determine the influence of complexation on in
Virginie Lhiaubet-Vallet et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 9(4), 552-558 (2010-04-01)
In most sunscreens, the presence of two UV filters usually leads to synergistic effects regarding both the final performance and photostabilization of the active principles. However, this may also result in an accelerated decomposition if a photoreaction occurs between the
Robert M Sayre et al.
Photochemistry and photobiology, 81(2), 452-456 (2004-11-25)
A major concern raised about photostability studies of sunscreen products is that the photodegradation of sunscreens does not readily translate into changes in product performance. This study examines the correlation between photochemical degradation of sunscreen agents and changes in protection
Woan-Ruoh Lee et al.
Toxicology letters, 211(2), 150-158 (2012-04-10)
While laser skin resurfacing is expected to result in reduced barrier function and increased risk of drug absorption, the extent of the increment has not yet been systematically investigated. We aimed to establish the skin permeation profiles of tetracycline and

質問

1–2/2 質問  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      役に立ちましたか?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      役に立ちましたか?

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