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D5879

Sigma-Aldrich

ジメチルスルホキシド

ReagentPlus®, ≥99.5%

別名:
メチルスルホキシド, DMSO
化学式:
(CH3)2SO
CAS番号:
分子量:
78.13
Beilstein:
506008
EC 番号:
MDL番号:
PubChem Substance ID:
NACRES:
NA.21

品質水準

200

蒸気密度

2.7 (vs air)

蒸気圧

0.42 mmHg ( 20 °C)

製品ライン

ReagentPlus®

アッセイ

≥99.5%

形態

liquid

自己発火温度

573 °F

expl. lim.

42 %, 63 °F

technique(s)

immunoblotting: suitable

不純物

≤0.1% water (Karl Fischer)

屈折率

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

溶解性

H2O: soluble(lit.)
acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)

密度

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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関連するカテゴリー

詳細

ジメチルスルホキシドは、水性溶媒と有機溶媒の両方に溶けやすい両親媒性の分子です。これは、非プロトン性溶媒として、また、有機合成における試薬としても一般的に使用されています。

アプリケーション

DMSOは、免疫ブロッティング技術に使用するため、市販の増強した化学発光キットに代わり得る化学発光試薬の調製用媒体として使用されています。

包装

100, 500 mL in glass bottle
1, 6×1, 2.5, 4 L in glass bottle
5, 10 L in poly drum
注: ガラスボトル入りD5879-1L/ポリボトル入りD5879-1L-D。

生物化学的/生理学的作用

DMSOは、有機および無機化学物質の工業用溶媒として使用できる高極性物質です。これは、生細胞の冷蔵中の保護剤としても使用されます。また、チオールおよびジスルフィドのスルホン酸への酸化にも有用です。

注意

容易に過冷却状態となり、室温で徐々に再融解します。凝固している場合は室温に放置すると、劣化させることなく液体に戻すことができます。

その他情報

ジメチルスルホキシドの混和性については、次のリンク先をご覧ください。
ジメチルスルホキシド混和性/非混和性表

法的情報

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

188.6 °F - closed cup

引火点(℃)

87 °C - closed cup

試験成績書(COA)

原産地証明書(COO)

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What is the molarity of Product D5879, Dimethyl sulfoxide?

    Pure solvents do not technically have a molarity (defined as moles of solute per liter of solution), since there is no solute distinct from the pure material. However, an effective molar concentration of 14.1M can be determined for this product, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

  6. The Dimethyl sulfoxide, Product D5879,  I ordered arrived as a solid. Is the product still acceptable?

    Sigma-Aldrich ships many products, including DMSO, at ambient temperature. As a result product D5879 might arrive as a solid depending on the weather conditions during shipment. The melting point of DMSO is 16-19°C. Therefore, if the solid is allowed to warm to room temperature, it will melt without any impact on the quality of the product.

  7. My application requires a dry solvent. How can I remove water that is present in Dimethyl sulfoxide, Product D5879?

    This product has a water content specification of not more than 0.1%, which may be low enough for your application. Other DMSO products may have more water present. Molecular sieves are typically zeolite compounds that strongly adsorb water and have carefully controlled pore sizes. If you would like, dried sieves may be placed into the bulk solvent container (about 5%-10% by volume) to remove most water.  Sigma-Aldrich offers 4 Å molecular sieves (e.g. product 334308), which would be effective in removing residual water from DMSO.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Julia L Zehr et al.
Biology of reproduction, 72(5), 1087-1094 (2004-12-31)
This study investigated whether prenatal androgen exposure, social rank, and body weight are factors regulating pubertal development in outdoor-housed female rhesus monkeys. Subjects' mothers received injections of testosterone enanthate (20 mg/ wk), flutamide (an androgen receptor blocker, 30 mg/kg twice
Lowe, O.G
The Journal of Organic Chemistry, 41 (1976)
Sun-A Ock et al.
Cell transplantation, 20(8), 1231-1239 (2011-02-08)
Dimethyl sulfoxide (DMSO), a commonly used cryoprotectant in cryopreservation procedures, is detrimental to viability of cells. In this view point, a comparative study was carried out to evaluate the effect of DMSO on porcine mesenchymal stem cells (pMSCs). We compared
M Bouquet et al.
Molecular reproduction and development, 40(1), 110-115 (1995-01-01)
In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to
Levent Keskintepe et al.
Journal of assisted reproduction and genetics, 26(11-12), 629-635 (2009-12-08)
Cryopreservation of blastocysts, especially those subjected to the trauma due to blastomere biopsy for the purposes of pre-implantation genetic screening (PGS), requires significant optimization. Laboratory and clinical outcomes were compared to determine the effect of two different cryopreservation techniques on

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