Merck

97617

Sigma-Aldrich

コレステロールα-D-グルコシド

≥98% (TLC)

別名:
αCG, コレステリルα-D-グルコピラノシド
Empirical Formula (Hill Notation):
C33H56O6
CAS番号:
分子量:
548.79
PubChem Substance ID:

アッセイ

≥98% (TLC)

形状

powder

光学活性

[α]/D 67.0±3.0°, c = 1 in pyridine

適合性

conforms to structure for Infrared spectrum

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@H](C2)CC[C@@]3(C)C2=CC[C@]4([H])[C@]3([H])CC[C@@]5(C)[C@@]4([H])CC[C@@]5([C@H](C)CCCC(C)C)[H]

InChI

1S/C33H56O6/c1-19(2)7-6-8-20(3)24-11-12-25-23-10-9-21-17-22(13-15-32(21,4)26(23)14-16-33(24,25)5)38-31-30(37)29(36)28(35)27(18-34)39-31/h9,19-20,22-31,34-37H,6-8,10-18H2,1-5H3/t20-,22+,23+,24-,25+,26+,27?,28-,29?,30+,31+,32+,33-/m1/s1

InChI key

FSMCJUNYLQOAIM-QIFAGWPJSA-N

類似品目との比較

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当該品目
T029928609700016P
α,β-Trehalose ≥98%

Sigma-Aldrich

T0299

α,β-トレハロース

cholesterol sulfate

Avanti

700016P

cholesterol sulfate

form

powder

form

crystalline powder

form

solid

form

powder

optical activity

[α]/D 67.0±3.0°, c = 1 in pyridine

optical activity

-

optical activity

[α]/D -49.0±3.0°, c = 0.5 in pyridine

optical activity

-

suitability

conforms to structure for Infrared spectrum

suitability

-

suitability

-

suitability

-

生物化学的/生理学的作用

コレステリルα-グルコシドは、H.ピロリ菌が介在する胃炎および前がん性萎縮性胃炎において重要です。

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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COAをリクエストする

Yuki Ito et al.
PloS one, 8(12), e78191-e78191 (2013-12-07)
Approximately 10-15% of individuals infected with Helicobacter pylori will develop ulcer disease (gastric or duodenal ulcer), while most people infected with H. pylori will be asymptomatic. The majority of infected individuals remain asymptomatic partly due to the inhibition of synthesis
Christian Wunder et al.
Nature medicine, 12(9), 1030-1038 (2006-09-05)
Helicobacter pylori infection causes gastric pathology such as ulcer and carcinoma. Because H. pylori is auxotrophic for cholesterol, we have explored the assimilation of cholesterol by H. pylori in infection. Here we show that H. pylori follows a cholesterol gradient
Hitomi Hoshino et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 59(1), 98-105 (2010-09-30)
Helicobacter pylori (H. pylori) is the causative pathogen underlying gastric diseases such as chronic gastritis and gastric cancer. Previously, the authors revealed that α1,4-linked N-acetylglucosamine-capped O-glycan (αGlcNAc) found in gland mucin suppresses H. pylori growth and motility by inhibiting catalytic
Masatomo Kawakubo et al.
Science (New York, N.Y.), 305(5686), 1003-1006 (2004-08-18)
Helicobacter pylori infects the stomachs of nearly a half the human population, yet most infected individuals remain asymptomatic, which suggests that there is a host defense against this bacterium. Because H. pylori is rarely found in deeper portions of the
Y Hirai et al.
Journal of bacteriology, 177(18), 5327-5333 (1995-09-01)
A chloroform-methanol-extracted lipid of Helicobacter pylori was studied. Three kinds of glycolipids, accounting for about 25% (wt/wt) of the total lipid, were detected and identified to be cholesteryl glucosides. The structures of two of them were determined to be cholesteryl-alpha-D-glucopyranoside

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