Merck
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A2383

Sigma-Aldrich

アデノシン 5'-三リン酸 二ナトリウム塩 水和物

Grade I, ≥99%, from microbial

Synonym(s):
ATP 二ナトリウム塩
Empirical Formula (Hill Notation):
C10H14N5Na2O13P3 · xH2O
CAS Number:
Molecular Weight:
551.14 (anhydrous basis)
EC Number:
MDL番号:
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51

由来生物

microbial

品質水準

タイプ

Grade I

アッセイ

≥99%

形状

powder

溶解性

H2O: 50 mg/mL

保管温度

−20°C

SMILES string

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

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This Item
A6419A7699A26209
biological source

microbial

biological source

microbial

biological source

microbial

biological source

-

assay

≥99%

assay

≥99% (HPLC)

assay

≥99% (HPLC)

assay

99%

form

powder

form

powder

form

powder

form

-

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL

solubility

H2O: 50 mg/mL, clear, colorless

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

アプリケーション

アデノシン-5′-三リン酸二ナトリウム塩は以下の用途に用いられています:
  • 種々の細菌培養におけるATPレベル測定用アデノシン三リン酸(ATP)標準溶液の調製に
  • 骨髄由来マクロファージ(BMDM)治療
  • コートマーβサブユニット(β-COP)の結合効果を検討するためのグアニンヌクレオチドフリーの調製液として

生物化学的/生理学的作用

P2プリン作動性アゴニストです。カルシウム活性化カリウムチャンネルの活性を増加させます。ATP依存性酵素系の基質です。
アデノシン5′-三リン酸(ATP)は、in vivoでのエネルギー貯蔵および代謝の中心的な構成要素です。ATPは、呼吸、生合成反応、能動輸送、および運動などの、数多くの細胞プロセスに使用されます。ATPは、細胞のシグナリングに関与する多くのキナーゼの基質であり、セカンドメッセンジャーである環状アデノシン一リン酸(cAMP)を生成するアデニル酸シクラーゼの基質です。ATPにより、代謝ポンプを駆動するための代謝エネルギーがもたらされます。幅広い酵素反応におけるコエンザイムとして機能します。

保管分類コード

11 - Combustible Solids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Faceshields, Gloves, type N95 (US)


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