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D4540

Sigma-Aldrich

ジメチルスルホキシド

≥99.5% (GC), suitable for plant cell culture

別名:
メチルスルホキシド, DMSO
化学式:
(CH3)2SO
CAS番号:
分子量:
78.13
Beilstein:
506008
EC 番号:
MDL番号:
PubChem Substance ID:
NACRES:
NA.71

品質水準

200

蒸気密度

2.7 (vs air)

蒸気圧

0.42 mmHg ( 20 °C)

アッセイ

≥99.5% (GC)

形態

liquid

自己発火温度

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | plant: suitable
cryopreservation: suitable

不純物

<0.1% water (Karl Fischer)

colorless

屈折率

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

溶解性

H2O: miscible (completely)

密度

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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アプリケーション

ジメチルスルホキシドは以下の用途に使用されています:
  • ビスフェノールA(BPA)の調製
  • 細胞増殖アッセイ(MTTアッセイ)
  • 化学感受性アッセイ
  • アポトーシスアッセイのようなすべての実験における溶媒対照
  • エトキシレゾルフィン-O -脱エチル化(EROD)アッセイ

包装

1 L in glass bottle
100, 500 mL in glass bottle

生物化学的/生理学的作用

有機溶媒であるDMSO(ジメチルスルホキシド)は、鎮痛、利尿、静菌、膜浸透性、抗炎症、血管拡張、コリンエステラーゼ阻害などいくつかの薬剤活性を持っています。本化合物は製材業の副産物であり、工業用溶剤として使用されます。また、DMSOは間質性膀胱炎および関節炎を治療する治療薬として働きます。

注意

容易に過冷却状態となり、室温で徐々に再融解します。凝固している場合は室温に放置すると、劣化させることなく液体に戻すことができます。

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

188.6 °F - closed cup

引火点(℃)

87 °C - closed cup

個人用保護具 (PPE)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

試験成績書(COA)

原産地証明書(COO)

  1. What is the molarity of DMSO?

    DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

  2. What is the DMSO dissolved in?

    DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

  3. Where does DMSO come from?

    DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

  4. What concentration of DMSO do I use in a cell freezing media?

    DMSO is usually used at 1-10%, depending on the cell line.  For the cell freezing media that we offer, it is used at 8.7% concentration.

  5. Does DMSO have any synthetic utility?

    DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

  6. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  7. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

  8. What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

  9. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  10. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  11. Is Dimethyl sulfoxide a sterile product?

    No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

  12. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  13. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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