GW22389F

Sigma-Aldrich

Anti-Chorionic Gonadotropin β Subunit (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

由来生物

chicken

品質水準

200

抗体製品の状態

affinity isolated antibody

antibody product type

primary antibodies

クローン

polyclonal

形態

buffered aqueous solution

species reactivity

human

manufacturer/tradename

Genway 15-288-22389F

アプリケーション

western blot: suitable

結合体

unconjugated

NCBIアクセッション番号

UniProtアクセッション番号

出荷済み

wet ice

保管温度

−20°C

Gene Information

human ... CGB(1082)

免疫原

Recombinant chorionic gonadotropin β 3 subunit
Immunogen Sequence: GI # 4502789, sequence 1-165

アプリケーション

Anti-Chorionic Gonadotropin ß Subunit (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生物化学的/生理学的作用

Choriogonadotropin subunit β (CG-β) is a protein encoded by the CGB gene in humans and belongs to glycoprotein hormone β chain family. It encodes the β 3 subunit of chorionic gonadotropin and consists of a unique carboxyl-terminal peptide (CTP) that has multiple O-linked glycans and extends serum half-life of the protein. CG-β expression may be seen in high-grade osteosarcoma. Its expression in classic seminoma (CS) is not limited to syncytiotrophoblastic cells.

物理的形状

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

RIDADR

NONH for all modes of transport

ドイツ水質汚染分類

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

試験成績書(COA)
原産地証明書(COO)
Anna F Lee et al.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 17(4), 278-285 (2014-05-27)
Survival rates have plateaued at 70% for osteosarcoma. Proteins ectopically produced by malignant tumors may provide insight into new therapeutic targets. Osteosarcomas secreting human chorionic gonadotropin (hCG) have been suggested to have a worse prognosis. We examined the frequency of...
Ondrej Hes et al.
Annals of diagnostic pathology, 18(2), 89-94 (2014-02-01)
The presence of human chorionic gonadotropin (hCG) positive syncytiotrophoblastic cells (STC) in classic seminoma (CS) is well documented. CS with extensive hCG positive, non-syncytiotrophoblastic tumour cells (without STC) is exceptionally rare. In this study, we present 15 such cases. 168...
Reut Gabay et al.
Molecular and cellular endocrinology, 382(2), 781-790 (2013-11-19)
CGβ subunits comprise a unique carboxyl-terminal peptide (CTP) that has multiple O-linked glycans and extends serum half-life of the protein. It has evolved by incorporating a previously untranslated region of the LHβ gene into the reading frame. Although CTP-like sequences...

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