The solubility of this product has been tested in ethanol at 1 mg/mL, and heating to 37°C may be required for complete solubilization. The solubility in DMSO has not been tested, but various sources indicate that this product is soluble in DMSO at a minimum of 20 mg/mL.
H0135
ヒドロコルチゾン
γ-irradiated, powder, BioXtra, suitable for cell culture
別名:
11β,17α,21-トリヒドロキシプレグナ-4-エン-3,20-ジオン, 17-ヒドロキシコルチコステロン, 4-プレグネン-11β,17α,21-トリオール-3,20-ジオン, ケンダルコンパウンドF, コルチゾール, ライヒシュタインサブスタンスM
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この商品について
実験式（ヒル表記法）:
C21H30O5
CAS番号:
分子量:
362.46
UNSPSC Code:
12352209
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-020-1
Beilstein/REAXYS Number:
1354819
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥80% (HPLC)
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InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
biological source
synthetic (organic)
sterility
γ-irradiated
product line
BioXtra
assay
≥80% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
mp
211-214 °C (lit.)
solubility
ethanol: 1 mg/mL, clear
shipped in
ambient
storage temp.
room temp
Quality Level
Gene Information
human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)
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当該品目 | H0888 | H3160 | H6909 |
|---|---|---|---|
| biological source synthetic (organic) | biological source soybean | biological source plant (wild yam) | biological source non-animal source |
| assay ≥80% (HPLC) | assay ≥98% | assay 97.0-102.0% dry basis | assay - |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 500 |
| product line BioXtra | product line BioReagent | product line - | product line BioXtra |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) cell culture | mammalian: suitable |
| form powder | form powder | form powder | form liquid |
General description
上皮系、内皮系の接着細胞培養に用いられるヒドロコルチゾンです。
Application
Biochem/physiol Actions
副腎皮質から分泌される主要なグルココルチコイドです。
副腎皮質から分泌される主要なグルココルチコイドです。コルチコステロンの3倍の抗炎症作用がありますが、Na+ 保持力は非常に低いです。
Physical form
粉末は室温で保存できます。ストック溶液は分注して凍結保存してください。凍結融解の繰り返しは避けてください。
Preparation Note
50 μg/mLのストック溶液を調製するには、無水エタノ-ル1 mLを添加し、穏和に撹拌して溶解させ、混合しながら滅菌培地19 mLを加えます。
Comparable product
signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
target_organs
Adrenal gland,Bone marrow
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
H0135-1MG: + H0135-BULK: + H0135PROC: + H0135-VAR: + H0135-1MG-PW: + H0135-PH: + H0135-1MG-IR:
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Oscar K Lee et al.
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Could I use DMSO as the solvent for hydrocortisone ?
1 回答-
役に立ちましたか？
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How long is the 50 μg/mL stock solution (1 mL absolute ethanol + 19 mL sterile medium) stable when stored in frozen aliquots at -20°C?
1 回答-
Unfortunately, the solution stability of this product at -20°C is not determined internally. However, various sources suggest frozen aliquots stored at -20°C are stable for at least 3-4 months. It is strongly recommend to protect the solution from light.
役に立ちましたか？
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What are the recommended storage conditions for stock solutions of item H0135, Hydrocortisone?
1 回答-
The stock solutions can be stored at 4°C and are stable for up to 1 month.
役に立ちましたか？
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