Merck
  • H4001
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H4001

Sigma-Aldrich

ヒドロコルチゾン

≥98% (HPLC)

Synonym(s):
11β,17α,21-トリヒドロキシプレグナ-4-エン-3,20-ジオン, 17-ヒドロキシコルチコステロン, 4-プレグネン-11β,17α,21-トリオール-3,20-ジオン, ケンダルコンパウンドF, コルチゾール, ライヒシュタインサブスタンスM
Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
Molecular Weight:
362.46
Beilstein:
1354819
EC Number:
MDL番号:
PubChem Substance ID:
NACRES:
NA.77

由来生物

synthetic (organic)

無菌性

non-sterile

アッセイ

≥98% (HPLC)

形状

powder

mp

211-214 °C (lit.)

溶解性

water: 0.28 g/L at 25 °C

application(s)

cell analysis

輸送温度

ambient

保管温度

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Inchi Key

JYGXADMDTFJGBT-VWUMJDOOSA-N

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This Item
PHR10141316004H1300000
Hydrocortisone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1014

ヒドロコルチゾン

Hydrocortisone United States Pharmacopeia (USP) Reference Standard

USP

1316004

ヒドロコルチゾン

Hydrocortisone European Pharmacopoeia (EP) Reference Standard

H1300000

ヒドロコルチゾン

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

-

form

-

form

-

solubility

water: 0.28 g/L at 25 °C

solubility

-

solubility

-

solubility

-

shipped in

ambient

shipped in

-

shipped in

-

shipped in

-

storage temp.

room temp

storage temp.

2-30°C

storage temp.

-

storage temp.

2-8°C

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

-

生物化学的/生理学的作用

副腎皮質から分泌される主要なグルココルチコイドです。コルチコステロンの3倍の抗炎症作用がありますが、Na+ 保持力は非常に低いです。

特徴および利点

この化合物は、Handbook of Receptor Classification and Signal Transduction(受容体分類およびシグナル伝達ハンドブック)のNuclear Receptors (Steroids)(核受容体[ステロイド])のページに示されています。ハンドブックの他のページを閲覧するには、ここをクリックしてください

ピクトグラム

Health hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Repr. 1A - STOT RE 2

保管分類コード

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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