HPA001762

Sigma-Aldrich

抗VIM ウサギ宿主抗体

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

別名:
抗ビメンチン抗体 ウサギ宿主抗体
Human Protein Atlas Number:

由来生物

rabbit

品質水準

100

抗体製品の状態

affinity isolated antibody

antibody product type

primary antibodies

クローン

polyclonal

製品ライン

Prestige Antibodies® Powered by Atlas Antibodies

形態

buffered aqueous glycerol solution

species reactivity

human, mouse

包装

antibody small pack of 25 μL

強化検証

orthogonal RNAseq
Learn more about Antibody Enhanced Validation

アプリケーション

immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:1000-1:2500

免疫原配列

FANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVES

結合体

unconjugated

主な業界

Research Pathology

UniProtアクセッション番号

出荷済み

wet ice

保管温度

−20°C

Gene Information

human ... VIM(7431)

詳細

Vimentin is a type III intermediary filament protein that is present in mesenchymal tissues. Vimentins regulate several cellular functions such as response to mechanical stress, cell shape, and cell movement. These proteins may also be involved in the pathogenesis of tissue fibrosis . Anti-VIM antibody is specific for VIM in humans.

免疫原

ビメンチンのPrEST(recombinant protein epitope signature tag)抗原リコンビナントタンパク質。

アプリケーション

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Anti-VIM antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using protein array and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige. Anti-VIM antibody is suitable for use in indirect immunofluorescence.

特徴および利点

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

関連事項

Corresponding Antigen APREST85020.

物理的形状

PBS溶液 (pH 7.2, 40%グリセロ-ル, 0.02%アジ化ナトリウム含有)

法的情報

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

storage_class_code

12 - Non Combustible Liquids

ドイツ水質汚染分類

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

試験成績書(COA)

原産地証明書(COO)

Sharada Sawant et al.
PloS one, 11(8), e0160615-e0160615 (2016-08-09)
To study multistep tumorigenesis process, there is a need of in-vitro 3D model simulating in-vivo tissue. Present study aimed to reconstitute in-vitro tissue models comprising various stages of neoplastic progression of tongue tumorigenesis and to evaluate the utility of these...
Maria Nilsson et al.
Scientific reports, 6, 19608-19608 (2016-01-26)
Lysyl oxidase (LOX) and LOX-like (LOXL) enzymes are key players in extracellular matrix deposition and maturation. LOX promote tumour progression and metastasis, but it may also have tumour-inhibitory effects. Here we show that orthotopic implantation of rat prostate AT-1 tumour...
In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome.
Taher, et al.
PLoS Pathogens, 16, e1008666-e1008666 (2021)
Takeshi Yamasaki et al.
International journal of oncology, 41(3), 805-817 (2012-07-07)
Many studies have recently suggested that microRNAs (miRNAs) contribute to the development of various types of human cancers as well as to their invasive and metastatic capacities. Previously, our miRNA expression signature of renal cell carcinoma (RCC) revealed that microRNA‑138...
Edward P Carter et al.
Breast cancer research : BCR, 19(1), 50-50 (2017-04-22)
3D modelling fulfils a critical role in research, allowing for complex cell behaviour and interactions to be studied in physiomimetic conditions. With tissue banks becoming established for a number of cancers, researchers now have access to primary patient cells, providing...

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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