There is no available information on the duration for which the product remains viable once reconstituted, as it was not tested for this purpose.
M3781
6α-メチルプレドニソロン 21-ヘミスクシネート ナトリウム塩
synthetic, ≥98.00% (TLC), Prednisolone derivative, lyophilized powder
別名:
6α-メチル-11β,17α,21-トリヒドロキシ-1,4-プレグナジエン-3,20-ジオン 21-ヘミスクシネート
ログインで組織・契約価格をご覧ください。
この商品について
化学式:
C26H33O8Na
CAS番号:
分子量:
496.53
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
219-156-8
MDL number:
スキップする
製品名
6α-メチルプレドニソロン 21-ヘミスクシネート ナトリウム塩, lyophilized powder
InChI
1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1
InChI key
FQISKWAFAHGMGT-SGJOWKDISA-M
SMILES string
[Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14
biological source
synthetic
sterility
non-sterile
assay
≥98.00% (TLC)
form
lyophilized powder
technique(s)
toxicology assay: suitable
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
Quality Level
Gene Information
human ... NR3C1(2908)
類似した製品をお探しですか？ 訪問 製品比較ガイド
関連するカテゴリー
1 of 4
当該品目 | H4881 | P8650 | 1435003 |
|---|---|---|---|
| form lyophilized powder | form powder | form powder | form - |
| assay ≥98.00% (TLC) | assay ≥90% (HPLC) | assay ≥97% | assay - |
| technique(s) toxicology assay: suitable | technique(s) - | technique(s) - | technique(s) - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level - |
| storage temp. room temp | storage temp. −20°C | storage temp. room temp | storage temp. - |
| solubility water: 50 mg/mL, clear, colorless to faintly yellow | solubility water: 50 mg/mL, clear, colorless to faintly yellow | solubility chloroform: methanol (1:1): 50 mg/mL, clear, colorless | solubility - |
Biochem/physiol Actions
プレドニソロンよりも若干半減期が長いグルココルチコイドです。
Physical form
凍結乾燥品 (リン酸バッファ-塩約5%含有)。
Application
6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.[1]
signalword
Danger
hcodes
pcodes
Hazard Classifications
Carc. 2 - Repr. 1B
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Basilar leptomeningitis in Vogt-Koyanagi-Harada disease.
Yince Loh
Neurology, 78(6), 438-439 (2012-02-09)
Hypoxia enhances glucocorticoid-induced apoptosis and cell cycle arrest via the PI3K/Akt signaling pathway in osteoblastic cells
Zou W, et al.
Journal of Bone and Mineral Metabolism, 33(6), 615-624 (2015)
Acute liver failure and aplastic anemia in an 11-year-old girl.
Ann Ming Yeh et al.
Digestive diseases and sciences, 56(8), 2237-2240 (2011-03-29)
Julio Urrutia et al.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 16(4), 439-442 (2011-04-30)
The effect of corticosteroids on spinal fusion healing has not yet been determined. To evaluate the effect of corticosteroids on lumbar spinal fusion we designed a randomized, placebo-controlled animal study using high-dose methylprednisolone sodium succinate, which is widely used in
Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy.
Sabrina Fourcade et al.
Archives of dermatology, 147(10), 1227-1228 (2011-10-19)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）