Merck
  • R8157
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R8157

Sigma-Aldrich

RSK4, 活性型, GSTタグ付加 ヒト

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
RPS6KA6
NACRES:
NA.32

リコンビナント

expressed in baculovirus infected Sf9 cells

品質水準

製品種目

PRECISIO® Kinase

アッセイ

≥70% (SDS-PAGE)

形状

buffered aqueous glycerol solution

specific activity

459-621 nmol/min·mg

分子量

~112 kDa

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−70°C

Gene Information

human ... RPS6KA6(27330)

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This Item
R1031S6698SRP5033
recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

specific activity

459-621 nmol/min·mg

specific activity

159-215 nmol/min·mg

specific activity

173-234 nmol/min·mg

specific activity

3.6-4.9 nmol/min·mg

mol wt

~112 kDa

mol wt

~108 kDa

mol wt

~130 kDa

mol wt

~95 kDa

UniProt accession no.

Q9UK32

UniProt accession no.

Q15418

UniProt accession no.

Q96SB4

UniProt accession no.

-

生物化学的/生理学的作用

RSK4は、増殖因子を介した細胞の増殖、生存や分化の刺激において重要な要素である90-kDaリボソームS6キナーゼファミリーに属します。RSK4は、ERKや3-ホスホイノシチド依存性プロテインキナーゼ-1(PDK1)による協調的なリン酸化によって活性化されます。多くの場合、RSK4はX連鎖性難聴3型(DFN3)、精神遅滞(MRX)、全脈絡膜萎縮(CHM)から成る隣接遺伝子症候群にかかわっています。RSK4は、脳と腎臓に最も豊富に発現しています。

物理的形状

50 mM Tris-HCl(pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25%グリセロール含有)。

法的情報

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Cartagena Act

カルタヘナ法

Certificate of Analysis

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Certificate of Origin

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