SAB1300063

Sigma-Aldrich

Anti-NCAPH2 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

別名:
Anti-Non-SMC condensin II complex, Anti-NCAPH2, Anti-Subunit H2
NACRES:
NA.41

由来生物

rabbit

品質水準

200

抗体製品の状態

IgG fraction of antiserum

antibody product type

primary antibodies

クローン

polyclonal

形態

buffered aqueous solution

species reactivity

human

アプリケーション

indirect ELISA: 1:1000
western blot: 1:100-1:500

結合体

unconjugated

NCBIアクセッション番号

UniProtアクセッション番号

出荷済み

dry ice

保管温度

−20°C

Gene Information

human ... NCAPH2(29781)

詳細

Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.

免疫原

NCAPH2 (NP_689512, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NCAPH2.

物理的形状

精製済みポリクローナル抗体のPBS溶液(0.09%(W/V)アジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

ドイツ水質汚染分類

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable

試験成績書(COA)
原産地証明書(COO)

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