The immunogen for anti-EID2 antibody: synthetic peptide derected towards the C terminal of human EID2
Eid2 interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation. It inhibits EP300 ihistone acetyltransferase activity. It acts as a repressor of TGFB/SMAD transcriptional responses. It may act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex.
Synthetic peptide located within the following region: QFLRHYLENYPIAPGRIQELEERRRRFVEACRAREAAFDIEYLRNPQRVD
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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