SAB2108050

Sigma-Aldrich

Anti-EEF1A1 antibody produced in rabbit

IgG fraction of antiserum

NACRES:
NA.41

由来生物

rabbit

品質水準

100

抗体製品の状態

IgG fraction of antiserum

antibody product type

primary antibodies

クローン

polyclonal

形態

buffered aqueous solution

分子量

50kDa

species reactivity

rabbit, rat, dog, horse, sheep, goat, bovine, mouse, guinea pig, human

濃度

0.5 mg - 1 mg/mL

アプリケーション

immunoblotting: suitable

結合体

unconjugated

NCBIアクセッション番号

UniProtアクセッション番号

出荷済み

wet ice

保管温度

−20°C

Gene Information

human ... EEF1A1(1915)

免疫原

Synthetic peptide directed towards the C terminal region of human EEF1A1

生物化学的/生理学的作用

EEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome.This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

シーケンス

Synthetic peptide located within the following region: IVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGK

物理的形状

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

ドイツ水質汚染分類

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

試験成績書(COA)
原産地証明書(COO)
Dongsheng Li et al.
Virology journal, 12, 118-118 (2015-08-06)
The cellular protein eukaryotic translation elongation factor 1A (eEF1A) binds to aminoacylated transfer RNAs and delivers them to the ribosome during translation. eEF1A also binds to RNA secondary structures present in genomes of several RNA viruses and plays important roles...
Molecular characterization and expression patterns of porcine eukaryotic elongation factor 1 A
H.L. Wang
Asian-Australasian Journal of Animal Sciences, 19(7), 953-953 (2006)
Toma Tebaldi et al.
Molecular cell, 71(2), 256-270 (2018-07-22)
The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral axon injury. HuD interacts with many mRNAs, altering both stability and translation efficiency. We generated a nucleotide resolution map of the HuD RNA interactome in motor neuron-like cells, identifying...

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