SAB2702270

Sigma-Aldrich

Monoclonal Anti-ARHGEF18 antibody produced in mouse

clone GT1972, affinity isolated antibody

別名:
P114-RhoGEF
NACRES:
NA.41

品質水準

100

由来生物

mouse

抗体製品の状態

affinity isolated antibody

antibody product type

primary antibodies

クローン

GT1972, monoclonal

形態

buffered aqueous solution

species reactivity

rat, human, mouse

濃度

1mg/mL

アプリケーション

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1,000
western blot: 1:500-1:3000

アイソタイプ

IgG2a

結合体

unconjugated

UniProtアクセッション番号

出荷済み

wet ice

保管温度

−20°C

Gene Information

human ... ARHGEF18(23370)

免疫原

Recombinant protein encompassing a sequence within the center region of human ARHGEF18.

アプリケーション

Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的/生理学的作用

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

その他情報

Purification: Affinity purified by Protein G

物理的形状

Phosphate-buffered saline, no preservative added.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

ドイツ水質汚染分類

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

試験成績書(COA)
原産地証明書(COO)

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