Merck
  • SML0224
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SML0224

Sigma-Aldrich

HI-6

≥98% (HPLC)

Synonym(s):
1-[[[4-(Aminocarbonyl)pyridinio]methoxy]methyl]-2-[(hydroxyimino)methyl]-pyridinium chloride, 4-Carbamoyl-1-[[[2-[(hydroxyimino)methyl]pyridinium-1-yl]methoxy]methyl]pyridinium dichloride, Asoxime chloride, HI 6, HI 6 chloride, HJ 6, Transant
Empirical Formula (Hill Notation):
C14H16N4O3 · 2Cl
CAS Number:
Molecular Weight:
359.21
MDL番号:
PubChem Substance ID:
NACRES:
NA.77

品質水準

アッセイ

≥98% (HPLC)

形状

powder

white to beige

溶解性

H2O: 15 mg/mL (clear solution)

輸送温度

wet ice

保管温度

−20°C

SMILES string

[Cl-].[Cl-].NC(=O)c1cc[n+](COC[n+]2ccccc2\C=N\O)cc1

InChI

1S/C14H14N4O3.2ClH/c15-14(19)12-4-7-17(8-5-12)10-21-11-18-6-2-1-3-13(18)9-16-20;;/h1-9H,10-11H2,(H-,15,19);2*1H

InChI key

QELSIJXWEROXOE-UHFFFAOYSA-N

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HI-6 ≥98% (HPLC)

Sigma-Aldrich

SML0224

HI-6

AM580 ≥98% (HPLC)

Sigma-Aldrich

A8843

Am 580

Sigma-Aldrich

Sigma-Aldrich

SML0796

HI-TOPK-032

IM-12 ≥98% (HPLC)

Sigma-Aldrich

SML0084

IM-12

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

powder

color

white to beige

color

-

color

orange to dark red

color

yellow-orange

solubility

H2O: 15 mg/mL (clear solution)

solubility

-

solubility

DMSO: 3 mg/mL, clear (warmed)

solubility

DMSO: ≥9 mg/mL

shipped in

wet ice

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

詳細

HI-6 functions as an antidote for treating intoxication caused by nerve agents. It acts as a potent drug in radiation protection and suppresses oxidative stress. HI-6 prevents the toxicity of the antineoplastic drug irinotecan.

生物化学的/生理学的作用

HI-6 is an efficient oxime cholinesterase reactivator that is used as an antidote for organophosphates (Ops) exposure.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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