SML0492

ザナミビル

≥98% (HPLC)

• Synonym(s): 4-グアニジノ-2,4-ジデオキシ-2,3-デヒドロ-N-アセチルノイラミン酸, 4-グアニジノ-Neu5Ac2en
• Empirical Formula (Hill Notation): C₁₂H₂₀N₄O₇
• CAS Number: 139110-80-8
• Molecular Weight: 332.31
• MDL番号: MFCD00866966
• PubChem Substance ID: 329825442
• NACRES: NA.77

Properties

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 光学活性: [α]/D +30 to +40°, c = 1 in H₂O
• 色: white to beige
• 溶解性: H₂O: 10 mg/mL, clear
• 保管温度: room temp
• SMILES string: CC(=O)N[C@@H]1[C@@H](NC(N)=N)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
• InChI: 1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
• InChI key: ARAIBEBZBOPLMB-UFGQHTETSA-N

Description

アプリケーション

Zanamivir has been used:

• as a neuraminidase inhibitor to study its effects on influenza A virus (IAV) like particles
• as a neuraminidase inhibitor to study its effects on lipopolysaccharide (LPS)-mediated pathology in sepsis
• as an antiviral to study its effects on influenza B virus by plaque reduction assay

生物化学的／生理学的作用

ザナミビルは、インフルエンザウイルスのノイラミニダーゼ阻害剤です。

Zanamivir exhibits therapeutic effects against influenza caused by influenza virus A and B.

Safety Information

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302 - H315 - H319 - H335
• 注意書き: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable