Merck
  • SML0817
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SML0817

Sigma-Aldrich

Pivmecillinam

≥98% (HPLC)

Synonym(s):
Amdinocillin pivoxil
Empirical Formula (Hill Notation):
C21H33N3O5S
CAS Number:
Molecular Weight:
439.57
EC Number:
MDL番号:
PubChem Substance ID:
NACRES:
NA.77

品質水準

アッセイ

≥98% (HPLC)

形状

powder

光学活性

[α]/D +215 to +245°, c = 1 in ethanol

white to beige

溶解性

DMSO: 5 mg/mL, clear (warmed)

保管温度

−20°C

SMILES string

CC1(C)[C@H](C(OCOC(C(C)(C)C)=O)=O)N2C([C@](/N=C/N3CCCCCC3)([H])[C@@]2([H])S1)=O

InChI

1S/C21H33N3O5S/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23/h12,14-15,17H,6-11,13H2,1-5H3/b22-12+/t14-,15+,17-/m1/s1

InChI key

NPGNOVNWUSPMDP-UTEPHESZSA-N

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assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

-

color

white to beige

color

white to brown

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

ethanol: soluble 25 mg/mL

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

2-8°C

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

アプリケーション

Pivmecillinam has been used to test its efficacy as a breast cancer stem cells (CSCs) targeting agent.

生物化学的/生理学的作用

Pivmecillinam is a β-lactam antibiotic and a pivaloyl-containing pro-drug. It belongs to the class of amidinopenicillin. Pivmecillinam is an oral anti-microbial agent that can be considered for treating E. coli urinary tract infection (UTI).
Pivmecillinam is a gram negative antibiotic, and inhibitor of penicillin-binding protein 2 (PBP2). Pivmecillinam has been shown to have synergistic effects with several antibiotics including novobiocin and rifampin in gram negative bacteria.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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