Merck
All Photos(1)

SML2350

Sigma-Aldrich

Ferroquine

≥98% (HPLC)

All Photos(1)
Synonym(s):
1-[[(7-Chloro-4-quinolinyl)amino]methyl]-2-[(dimethylamino)methyl]-ferrocene, 7-Chloro-4-(((2-((dimethylamino)methyl)ferrocenyl)methyl)amino)quinoline, Ferrochloroquine, SSR 97193
Empirical Formula (Hill Notation):
C23H24ClFeN3
CAS Number:
185055-67-8
Molecular Weight:
433.75
NACRES:
NA.77

アッセイ

≥98% (HPLC)

形状

powder

保管条件

desiccated

色

yellow to brown

溶解性

DMSO: 2 mg/mL, clear

保管温度

2-8°C

SMILES string

CN(C)C[C]1[C]C[C][C]1CNC2=C(C=CC(Cl)=C3)C3=NC=C2.[C]4[C][C][C]C4.[Fe]

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SML0583F408D7783
Ferroquine ≥98% (HPLC)

Sigma-Aldrich

SML2350

Ferroquine

Ferrostatin-1 ≥95% (HPLC)

Sigma-Aldrich

SML0583

フェロスタチン-1

Ferrocene 98%

Sigma-Aldrich

F408

フェロセン

Pyrroloquinoline quinone ≥95.0% (HPLC)

Sigma-Aldrich

D7783

ピロロキノリンキノン

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

98%

assay

≥95.0% (HPLC)

form

powder

form

powder

form

-

form

powder

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

color

yellow to brown

color

, faint purple to brown

color

-

color

red to deep red

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

生物化学的／生理学的作用

Ferroquine (SSR 97193) is an antimalarial chloroquine analog effective against chloroquine-resistant Plasmodium falciparum. Ferroquine is thought to act by producing oxidative stress and by inhibiting the formation of hemozoin, produced by Malaria parasites as a disposal product of heme, which would otherwise be toxic to the Plasmodium cells.

ピクトグラム

Exclamation mark
GHS07

シグナルワード

Warning

危険有害性情報

H315 - H319 - H335

危険有害性の分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

ターゲットの組織

Respiratory system

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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