SML2450

BIIE 0246 hydrochloride

≥98% (HPLC)

• Synonym(s): AR-H 053591 hydrochloride, BIIE-0246 hydrochloride, N-[(1S)-4-[(Aminoiminomethyl)amino]-1-[[[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino]carbonyl]butyl]-1-[2-[4-(6,11-dihydro-6-oxo-5H-dibenz[b,e]azepin-11-yl)-1-piperazinyl]-2-oxoethyl]cyclopentaneacetamide
• Empirical Formula (Hill Notation): C₄₉H₅₇N₁₁O₆ · xHCl
• CAS Number: 246146-55-4
• Molecular Weight: 896.05 (free base basis)

Properties

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C

Description

生物化学的／生理学的作用

BIIE0246 is a high-affinity, competitive non-peptide antagonist for the neuropeptide Y (NPY) Y2 receptor (K_i = 8-15 nM). BIIE0246 potently blocks NPY effects in rat hippocampus.

Safety Information

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable