- SML2522
All Photos(1)
SML2522
Diprovocim-1
≥98% (HPLC)
All Photos(1)
Synonym(s):
(3S,3′S,4S,4′S)-1,1′-(1,4-Phenylenedicarbonyl)bis[N-[(1S,2R)-2-phenylcyclopropyl]-3,4-pyrrolidinedicarboxamide, 3,4-Pyrrolidinedicarboxamide, 1,1′-(1,4-phenylenedicarbonyl)bis[N-[(1S,2R)-2-phenylcyclopropyl]-, (3S,3′S,4S,4′S)-
Empirical Formula (Hill Notation):
C56H56N6O6
CAS Number:
Molecular Weight:
909.08
Recommended Products
アッセイ
≥98% (HPLC)
形状
powder
色
white to beige
溶解性
DMSO: 2 mg/mL, clear
保管温度
2-8°C
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This Item | W524905 | 64128 | 45459 |
|---|---|---|---|
| assay ≥98% (HPLC) | assay - | assay ≥98.0% (HPLC) | assay - |
| form powder | form - | form - | form - |
| color white to beige | color - | color - | color - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
生物化学的／生理学的作用
Diprovocim-1 is a potent agonist of toll-like receptors TLR2 and TLR1 with an EC50 value of 100 pM. Diprovocim-1 was shown to synergize with anti-PD-L1 treatment, inhibiting tumor growth, generating long-term antitumor memory, and curing or prolonging survival of mice engrafted with the murine melanoma B16-OVA.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
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