Merck
  • SML2670
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SML2670

Sigma-Aldrich

BAY-8002

≥98% (HPLC)

Synonym(s):
2-(2-chloro-5-(phenylsulfonyl)benzamido)benzoic acid, 2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]-benzoic acid
Empirical Formula (Hill Notation):
C20H14ClNO5S
CAS Number:
Molecular Weight:
415.85
MDL番号:

アッセイ

≥98% (HPLC)

形状

powder

white to beige

溶解性

DMSO: 2 mg/mL, clear

保管温度

2-8°C

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BAY-8002 ≥98% (HPLC)

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BAY 60-6583 ≥98% (HPLC)

Sigma-Aldrich

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BAY 60-6583

BAY-899 ≥98% (HPLC)

Sigma-Aldrich

SML2890

BAY-899

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

color

white to beige

color

white to beige

color

white to beige

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 1 mg/mL, clear

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

生物化学的/生理学的作用

BAY-8002 is an orally available, potent and selective inhibitor of lactate transporter MCT1 (monocarboxylate transporter 1; SLC16A1) that potently inhibits bidirectional lactate transport. BAY-8002 exhibits antiproliferative activity in numerous cancer cell lines. BAY-8002 induces accumulation of lactate and significantly inhibits tumor growth in mice model. It does not cause tumor regression.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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