SML2983

Vandetanib

≥98% (HPLC)

• Synonym(s): N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine, N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine, ZD6474
• Empirical Formula (Hill Notation): C₂₂H₂₄BrFN₄O₂
• CAS Number: 443913-73-3
• Molecular Weight: 475.35
• MDL番号: MFCD07772346

Properties

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C

Description

包装

5, 25 mg

生物化学的／生理学的作用

Vandetanib is an orally active and potent inhibitor of vascular endothelial growth factor receptor receptor 2 (VEGFR2) kinase activity that is used to treat medullary thyroid cancer. Vandetanib also inhibits epidermal growth factor receptor (EGFR), and RET tyrosine kinases.

Safety Information

• ピクトグラム: GHS07,GHS08,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302 - H361d - H373 - H410
• 注意書き: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2
• ターゲットの組織: Gastrointestinal tract
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable