Merck
  • SML3093
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SML3093

Sigma-Aldrich

2′-MeCCPA

≥98% (HPLC)

All Photos(1)
Synonym(s):
2′-Me-CCPA, 2-Chloro-2′-C-methyl-N6-cyclopentyladenosine, 2-Chloro-N-cyclopentyl-2′-C-methyladenosine
Empirical Formula (Hill Notation):
C16H22ClN5O4
CAS Number:
205171-12-6
Molecular Weight:
383.83

品質水準

100

アッセイ

≥98% (HPLC)

形状

powder

色

white to beige

溶解性

DMSO: 2 mg/mL, clear

保管温度

2-8°C

InChI

1S/C16H22ClN5O4/c1-16(25)11(24)9(6-23)26-14(16)22-7-18-10-12(19-8-4-2-3-5-8)20-15(17)21-13(10)22/h7-9,11,14,23-25H,2-6H2,1H3,(H,19,20,21)

InChI key

MMPAUXMIDJWGFO-UHFFFAOYSA-N

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SML3093

2′-MeCCPA

MOCPAC ≥95% (HPLC), solid

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PZ0255

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Sigma-Aldrich

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MEPB

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

powder

color

white to beige

color

-

color

white to beige

color

white to beige

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: soluble 21 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

生物化学的／生理学的作用

2′-MeCCPA is a potent and A1-selective adenosine receptor agonist (Ki = 1.8 nM/bovine A1, 3.9 μM/bovine A2a, 5.0 μM/rat A3). 2′-MeCCPA inhibits 100 μM forskolin-induced adenylate cyclase activity in rat cortical membrane preparations (IC50 = 13.1 nM; ECmax = 15.1% inhibition) without antagonist potency against A1 agonist CHA (N6-cyclohexyladenosine).

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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Certificate of Origin

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