Merck
  • SML3110
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SML3110

Sigma-Aldrich

CRANAD-3

≥98% (HPLC)

Synonym(s):
(T-4)-[(1E,6E)-1,7-Bis[6-(diethylamino)-3-pyridinyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoroboron, CRANAD 3
Empirical Formula (Hill Notation):
C25H31BF2N4O2
CAS Number:
Molecular Weight:
468.35

品質水準

アッセイ

≥98% (HPLC)

形状

powder

保管条件

desiccated

gray to black

溶解性

DMSO: 2 mg/mL, clear (warmed)

保管温度

2-8°C

SMILES string

FB(O1)(F)O=C(/C=C/C2=CN=C(N(CC)CC)C=C2)C=C1/C=C/C3=CC=C(N(CC)CC)N=C3

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CRANAD-3 ≥98% (HPLC)

Sigma-Aldrich

SML3110

CRANAD-3

Sigma-Aldrich

Sigma-Aldrich

SML0842

CRANAD 2

Crocetin phyproof® Reference Substance

PHL86280

Crocetin

Crocetin ≥98% (HPLC)

Sigma-Aldrich

SML3255

Crocetin

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥90.0% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

-

form

powder

storage condition

desiccated

storage condition

desiccated

storage condition

-

storage condition

-

color

gray to black

color

, dark blue to black

color

-

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

solubility

DMSO: 0.2 mg/mL, clear (warmed)

solubility

-

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

生物化学的/生理学的作用

CRANAD-3, a curcumin analog, is a brain barrier penetrant smart NIRF (near-infrared) probe for both soluble and insoluble Aβ (amyloid beta) species in vivo. CRANAD-3 could be used to monitor the decrease in Aβs after drug treatment in transgenic AD (APP/PS1) mice. CRANAD-3 is suitable for in vivo dually-amplify signal via chemiluminescence resonance energy transfer (DAS-CRET) with ADLumin-1 a brain blood barrier penetrant smart chemiluminescence probe for Aβs

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

Certificate of Analysis

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Certificate of Origin

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