Effect of peroxiredoxin II on the quality and mitochondrial activity of pre-implantation bovine embryos.
Fakruzzaman M et al
Animal Reproduction Science, 159, 172-183 (2015)
Lía M Randall et al.
The Journal of biological chemistry, 289(22), 15536-15543 (2014-04-11)
Peroxiredoxins (Prx) are efficient thiol-dependent peroxidases and key players in the mechanism of H2O2-induced redox signaling. Any structural change that could affect their redox state, oligomeric structure, and/or interaction with other proteins could have a significant impact on the cascade...
Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
Salzano S, Checconi P, Hanschmann EM, et al.
Proceedings of the National Academy of Sciences of the USA, 111(33), 12157-12162 (2014)
Weidong Lu et al.
Molecular and cellular biochemistry, 387(1-2), 261-270 (2013-11-16)
Peroxiredoxin 2 (Prdx2) is a member of the peroxiredoxin family, which is responsible for neutralizing reactive oxygen species. Prdx2 has been found to be elevated in several human cancer cells and tissues, including colorectal cancer (CRC), and it influences diverse...
Doo Jae Lee et al.
Cancer research, 73(15), 4744-4757 (2013-06-12)
In melanoma, transition to the vertical growth phase is the critical step in conversion to a deadly malignant disease. Here, we offer the first evidence that an antioxidant enzyme has a key role in this transition. We found that the...