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Cell and developmental biology research
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3Dオルガノイド培養：発生と疾患の新しいin vitroモデル
オルガノイド培養用製品により、組織または幹細胞に由来する3Dの脳、腸、肺および腫瘍のオルガノイドモデルを作成できます。
3D細胞培養ツールおよび技術
3D細胞培養の概要2D細胞培養と3D細胞培養の比較、3D細胞培養の利点、3D細胞培養技術について紹介します。
胃腸管オルガノイドバイオバンク
メルクの患者由来オルガノイドバイオバンクでは、50人を超える患者由来のヒト腸オルガノイドをラインナップしています。さまざまな年齢、性別、由来組織や疾患のオルガノイドが利用可能です（正常、腫瘍、潰瘍性大腸炎）。
BPAフリー培養培地用の超純水
Milli-Q®装置から得られる超純水はBPAを含まず、発生学的研究に適しており、内分泌かく乱物質の干渉を最小限に抑えることが示されています。
Epigenetics Overview
Epigenetics is a term coined to describe changes that are not mutation based but can still be passed on from generation to generation. Genes that are activated or repressed without any change in DNA sequence are epigenetically controlled. Epigenetic modifications
Small RNA and miRNA (microRNA) Sequencing
A review on reducing miRNA and other small RNAs sequencing bias with RealSeq®-AC RNA library preparation on the Illumina® RNA sequencing platform.
Peptide Stability and Potential Degradation Pathways
To prevent or minimize peptide degradation we recommend storing the peptide in lyophilized form at –20 °C or –80 °C. Once in solution, the peptide/protein should be stored frozen in individual aliquots to avoid freeze-thaw cycles. Also, prolonged exposure to
Epigenetics Overview
Epigenetics is a term coined to describe changes that are not mutation based but can still be passed on from generation to generation. Genes that are activated or repressed without any change in DNA sequence are epigenetically controlled. Epigenetic modifications
Handling and Storage Guidelines for Peptides and Proteins
Handling and Storage Guidelines for Peptides and Proteins
Fibroblast Growth Factor Family (FGF)
Fibroblast growth factors in cell culture and various growth factors for your research
3D Cell Culture Tools and Techniques
3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models
Long-Term Live Cell Tracking of Cancer and Stem Cells Using a Biocompatible Fluorescent Nanoparticle Based Upon Aggregation Induced Emission (AIE Dot) Nanotechnology
Biocompatible organic fluorescent nanoparticles (AIE Dots) that can be used to label cells and vasculature for long-term live cell tracking and tracing experiments.
Canonical Wnt / β-Catenin Signaling
We review the Wnt signaling pathway (also, canonical Wnt or beta (β)-catenin pathway) and provide links to related products at sigmaaldrich.com.
Injectable Hydrogels for Tissue Regeneration
Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.
3D Organoid Culture: New In Vitro Models of Development and Disease
Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.
Small RNA and miRNA (microRNA) Sequencing
A review on reducing miRNA and other small RNAs sequencing bias with RealSeq®-AC RNA library preparation on the Illumina® RNA sequencing platform.
What is Hyaluronan?
Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.
Vascular Endothelial Growth Factors (VEGF)
VEGF-A stimulates blood vessel growth via endothelial cell proliferation, migration, and survival during embryonic development.
Ultrapure Water for BPA-free Culture Media
Ultrapure water from Milli-Q® system shown free of BPA, suitable for embryology research, minimizing endocrine disruptor interference.
Properties of Mononuclear Cells Isolated by the Ficoll-Paque Method
The effects of the mononuclear cell separation method described by Bøyum procedure are noted below, since research situations may arise in which they are significant.
Angiogenesis Assays
Cell based angiogenesis assays to analyze new blood vessel formation for applications of cancer research, tissue regeneration and vascular biology.
Solubility Guidelines for Peptides
Improper solubilization can potentially result in loss of the peptide/protein and result in failure of the experiment.
Pluripotent and Multipotent Stem Cells
Read types of stem cells including multipotent stem cells, Pluripotent stem cells and iPSCs and their applications in basic stem cell research, stem cell therapy and disease modelling
Oxygen & Nitric Oxide Probes
Our company's Detection Chelators and Ion Probes products are reviewed including oxygen and NO probe products, oxygen probes and NO probes.
Lipopolysaccharides for Research – Structure, Function & Applications
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
Gastrointestinal Organoid Biobank
Browse over 50 patient-derived human intestinal organoids from our PDO biobank. Various ages, sex, tissue origin and diseases available (normal, tumor organoids, ulcerative colitis).
Discover Bioactive Small Molecules for Cell Cycle
Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.
Collagenase Blends for Gentle Tissue Dissociation
Discover pre-mixed collagenase enzyme blends with DNase I, Dispase II, Elastase, and Hyaluronidase and gently dissociate animal tissues in vitro.