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SCT039

Sigma-Aldrich

BioTracker Green H2O2 Live Cell Dye

Live cell imaging probe for detection of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) in live cells.

Synonym(s):

BioTracker H₂O₂ Dye, Green Cell Dye

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.47

form

lyophilized

application(s)

cell analysis

detection method

fluorometric

Related Categories

General description

Hydrogen peroxide (H2O2) is involved in therapeutic processes such as wound healing, anti-bacterial defense, stem cell proliferation, and an adaptive response in astrocytes that leads to neuronal protection. However, over-production of H2O2 exerts toxic effects on the cell and its surrounding environment. Over-production of H2O2 is connected to serious pathological conditions such as cancer, ageing, diabetes, and neurodegenerative diseases.BioTracker Green H2O2 live cell dye is a fluorescent probe that fluoresces upon reaction with H2O2 , but does not react with other ROS such as hydroxyradical (-OH), superoxide (O2-), hypochlorous acid (HOCl), singlet oxygen (1O2), and nitric oxide (NO). This dye is cell permeable and initially has low reactivity with H2O2 but it is quickly hydrolyzed by intracellular esterases to generate a reactive and cell impermeable product that fluoresces upon reaction with H2O2. Spectral PropertiesAbsorbance (max): 492 nmEmission (max): 516 nm (Green)Research Categories:InflammationLive Cell Dye

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

WGK

WGK 3

Flash Point(F)

604.2 °F

Flash Point(C)

317.9 °C


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