ACHE
acetylcholinesterase
동의어:
ACEE, ARACHE, N-ACHE, YT
종:
Human ACHE (43), Mouse Ache (11423), Rat Ache (83817), domestic guinea pig Ache (100422792), sheep ACHE (101123006), cow ACHE (540446), domestic cat ACHE (493674), Zebrafish ache (114549), chicken ACHE (396388), naked mole-rat Ache (101705724)
UniProtKB ID:
Clone ID:
- Human(43) Summary: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
- Mouse(11423) acetylcholinesterase
- Rat(83817) acetylcholinesterase
- domestic guinea pig(100422792) acetylcholinesterase
- sheep(101123006) acetylcholinesterase
- cow(540446) acetylcholinesterase
- domestic cat(493674) acetylcholinesterase
- Zebrafish(114549) acetylcholinesterase
- chicken(396388) acetylcholinesterase
- naked mole-rat(101705724) acetylcholinesterase
- dog(489828) acetylcholinesterase
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Antibodies
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Anti-Acetylcholinesterase Antibody, clone AE-1, clone AE-1, Chemicon®, from mouse,
종별 반응성
bovine, canine, chicken, guinea pig, human, monkey
응용분야
ELISA
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Anti-ACHE antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rat
응용분야
western blot
Anti-ACHE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
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human
응용분야
immunofluorescence
Anti-ACHE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
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cat, human, mouse, rabbit, rat
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ELISA
flow cytometry
immunofluorescence
western blot
flow cytometry
immunofluorescence
western blot
Small Molecule - Inhibitor
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Kits
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Proteins
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Acetylcholinesterase human, recombinant, expressed in HEK 293 cells, lyophilized powder, ≥1,000 units/mg protein (BCA),
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human
esiRNA
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